SCOPe 2.08: Domain d1djwb3: 1djw B:299-625

Lineage for d1djwb3 (1djw B:299-625)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.18: PLC-like phosphodiesterases [51695] (4 families)

5. Family c.1.18.1: Mammalian PLC [51696] (2 proteins)

6. Protein Phospholipase C isozyme D1 (PLC-D1) [51697] (1 species)

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [51698] (11 PDB entries)

8. Domain d1djwb3: 1djw B:299-625 [29590]
   Other proteins in same PDB: d1djwa1, d1djwa2, d1djwb1, d1djwb2
   complexed with act, ca, cip

Details for d1djwb3

PDB Entry: 1djw, 2.45 Å

PDB Description: phosphoinositide-specific phospholipase c-delta1 from rat complexed with inositol-2-methylene-1,2-cyclic-monophosphonate

PDB Compounds: (B:) phosphoinositide-specific phospholipase c, isozyme delta1

SCOPe Domain Sequences for d1djwb3:

Sequence, based on SEQRES records:

>d1djwb3 c.1.18.1 (B:299-625) Phospholipase C isozyme D1 (PLC-D1) {Norway rat (Rattus norvegicus) [TaxId: 10116]}
dqplshylvssshntylledqltgpssteayiralckgcrcleldcwdgpnqepiiyhgy
tftskilfcdvlrairdyafkaspypvilslenhcsleqqrvmarhlrailgpilldqpl
dgvttslpspeqlkgkillkgkklggllpaggengseatdvsdeveaaemedeavrsqvq
hkpkedklklvpelsdmiiycksvhfggfsspgtsgqafyemasfsesralrllqesgng
fvrhnvsclsriypagwrtdssnyspvemwnggcqivalnfqtpgpemdvylgcfqdngg
cgyvlkpaflrdpnttfnsraltqgpw

Sequence, based on observed residues (ATOM records):

>d1djwb3 c.1.18.1 (B:299-625) Phospholipase C isozyme D1 (PLC-D1) {Norway rat (Rattus norvegicus) [TaxId: 10116]}
dqplshylvssshntylledqltgpssteayiralckgcrcleldcwdgpnqepiiyhgy
tftskilfcdvlrairdyafkaspypvilslenhcsleqqrvmarhlrailgpilldqpl
dgvttslpspeqlkgkillkgkklggldklklvpelsdmiiycksvhfggfsspgtsgqa
fyemasfsesralrllqesgngfvrhnvsclsriypagwrtdssnyspvemwnggcqiva
lnfqtpgpemdvylgcfqdnggcgyvlkpaflrdpnttfnsraltqgpw

Timeline for d1djwb3:

• d1djwb3 first appeared (with stable ids) in SCOP 1.55
  
• d1djwb3 appears in SCOPe 2.07