Lineage for d3tl5a5 (3tl5 A:143-143)

  1. Root: SCOPe 2.07
  2. 2598798Class l: Artifacts [310555] (1 fold)
  3. 2598799Fold l.1: Tags [310573] (1 superfamily)
  4. 2598800Superfamily l.1.1: Tags [310607] (1 family) (S)
  5. 2598801Family l.1.1.1: Tags [310682] (2 proteins)
  6. 2605870Protein N-terminal Tags [310894] (1 species)
  7. 2605871Species Synthetic [311501] (14103 PDB entries)
  8. 2618029Domain d3tl5a5: 3tl5 A:143-143 [295522]
    Other proteins in same PDB: d3tl5a1, d3tl5a2, d3tl5a3, d3tl5a4
    complexed with 980

Details for d3tl5a5

PDB Entry: 3tl5 (more details), 2.79 Å

PDB Description: Discovery of GDC-0980: a Potent, Selective, and Orally Available Class I Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Kinase Inhibitor for the Treatment of Cancer
PDB Compounds: (A:) phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

SCOPe Domain Sequences for d3tl5a5:

Sequence; same for both SEQRES and ATOM records: (download)

>d3tl5a5 l.1.1.1 (A:143-143) N-terminal Tags {Synthetic}

SCOPe Domain Coordinates for d3tl5a5:

Click to download the PDB-style file with coordinates for d3tl5a5.
(The format of our PDB-style files is described here.)

Timeline for d3tl5a5: