SCOPe 2.06: Domain d3ik3b2: 3ik3 B:228-228

Lineage for d3ik3b2 (3ik3 B:228-228)

1. Root: SCOPe 2.06

2. Class l: Artifacts [310555] (1 fold)

3. Fold l.1: Tags [310573] (1 superfamily)

4. Superfamily l.1.1: Tags [310607] (1 family)

5. Family l.1.1.1: Tags [310682] (2 proteins)

6. Protein N-terminal Tags [310894] (1 species)

7. Species Synthetic [311501] (10810 PDB entries)

8. Domain d3ik3b2: 3ik3 B:228-228 [293027]
   Other proteins in same PDB: d3ik3a1, d3ik3b1
   complexed with 0li; mutant

Details for d3ik3b2

PDB Entry: 3ik3, 1.9 Å

PDB Description: ap24534, a pan-bcr-abl inhibitor for chronic myeloid leukemia, potently inhibits the t315i mutant and overcomes mutation-based resistance

PDB Compounds: (B:) Proto-oncogene tyrosine-protein kinase ABL1

SCOPe Domain Sequences for d3ik3b2:

Sequence; same for both SEQRES and ATOM records:

>d3ik3b2 l.1.1.1 (B:228-228) N-terminal Tags {Synthetic}
g

Timeline for d3ik3b2:

• d3ik3b2 is new in SCOPe 2.06-stable
  
• d3ik3b2 appears in SCOPe 2.07
  
• d3ik3b2 appears in the current release, SCOPe 2.08