SCOPe 2.08: Domain d3ik3a2: 3ik3 A:228-228

Lineage for d3ik3a2 (3ik3 A:228-228)

1. Root: SCOPe 2.08

2. Class l: Artifacts [310555] (1 fold)

3. Fold l.1: Tags [310573] (1 superfamily)

4. Superfamily l.1.1: Tags [310607] (1 family)

5. Family l.1.1.1: Tags [310682] (2 proteins)

6. Protein N-terminal Tags [310894] (1 species)

7. Species Synthetic [311501] (15360 PDB entries)

8. Domain d3ik3a2: 3ik3 A:228-228 [293026]
   Other proteins in same PDB: d3ik3a1, d3ik3b1
   complexed with 0li; mutant

Details for d3ik3a2

PDB Entry: 3ik3, 1.9 Å

PDB Description: ap24534, a pan-bcr-abl inhibitor for chronic myeloid leukemia, potently inhibits the t315i mutant and overcomes mutation-based resistance

PDB Compounds: (A:) Proto-oncogene tyrosine-protein kinase ABL1

SCOPe Domain Sequences for d3ik3a2:

Sequence; same for both SEQRES and ATOM records:

>d3ik3a2 l.1.1.1 (A:228-228) N-terminal Tags {Synthetic}
g

Timeline for d3ik3a2:

• d3ik3a2 first appeared in SCOPe 2.06
  
• d3ik3a2 appears in SCOPe 2.07