SCOPe 2.08: Domain d1zfja1: 1zfj A:2-94,A:221-492

Lineage for d1zfja1 (1zfj A:2-94,A:221-492)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.5: Inosine monophosphate dehydrogenase (IMPDH) [51412] (2 families)
   The phosphate moiety of substrate binds in the 'common' phosphate-binding site

5. Family c.1.5.1: Inosine monophosphate dehydrogenase (IMPDH) [51413] (1 protein)

6. Protein Inosine monophosphate dehydrogenase (IMPDH) [51414] (8 species)

7. Species Streptococcus pyogenes [TaxId:1314] [51416] (1 PDB entry)

8. Domain d1zfja1: 1zfj A:2-94,A:221-492 [28638]
   Other proteins in same PDB: d1zfja4
   contains two CBS domains inserted into the common fold
   complexed with imp

Details for d1zfja1

PDB Entry: 1zfj, 1.9 Å

PDB Description: inosine monophosphate dehydrogenase (impdh; ec 1.1.1.205) from streptococcus pyogenes

PDB Compounds: (A:) inosine monophosphate dehydrogenase

SCOPe Domain Sequences for d1zfja1:

Sequence, based on SEQRES records:

>d1zfja1 c.1.5.1 (A:2-94,A:221-492) Inosine monophosphate dehydrogenase (IMPDH) {Streptococcus pyogenes [TaxId: 1314]}
snwdtkflkkgytfddvllipaeshvlpnevdlktkladnltlnipiitaamdtvtgskm
aiaiaragglgvihknmsiteqaeevrkvkrseXgrllvaaavgvtsdtferaealfeag
adaividtahghsagvlrkiaeirahfpnrtliagniataegaralydagvdvvkvgigp
gsicttrvvagvgvpqvtaiydaaavareygktiiadggikysgdivkalaaggnavmlg
smfagtdeapgeteiyqgrkyktyrgmgsiaamkkgssdryfqgsvneanklvpegiegr
vaykgaasdivfqmlggirsgmgyvgagdiqelhenaqfvemsgaglieshphdvqitne
apnysv

Sequence, based on observed residues (ATOM records):

>d1zfja1 c.1.5.1 (A:2-94,A:221-492) Inosine monophosphate dehydrogenase (IMPDH) {Streptococcus pyogenes [TaxId: 1314]}
snwdtkflkkgytfddvllipaeshvlpnevdlktkladnltlnipiitaamdtvtgskm
aiaiaragglgvihknmsiteqaeevrkvkrseXgrllvaaavgvtsdtferaealfeag
adaividtahghsagvlrkiaeirahfpnrtliagniataegaralydagvdvvkvgigp
gsicttrvvagvgvpqvtaiydaaavareygktiiadggikysgdivkalaaggnavmlg
smfagtdeapgeteiyqgrkyktyrgmgsiaamkknklvpegiegrvaykgaasdivfqm
lggirsgmgyvgagdiqelhenaqfvemsgaglieshphdvqitneapnysv

Timeline for d1zfja1:

• d1zfja1 first appeared (with stable ids) in SCOP 1.55
  
• d1zfja1 appears in SCOPe 2.07