SCOPe 2.08: Domain d4x5fb1: 4x5f B:1-159

Lineage for d4x5fb1 (4x5f B:1-159)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
   3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest

4. Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families)

5. Family c.71.1.0: automated matches [191485] (1 protein)
   not a true family

6. Protein automated matches [190777] (28 species)
   not a true protein

7. Species Escherichia coli [TaxId:83333] [267798] (11 PDB entries)

8. Domain d4x5fb1: 4x5f B:1-159 [280483]
   Other proteins in same PDB: d4x5fb2
   automated match to d3jw3a_
   complexed with bme, fol, nap

Details for d4x5fb1

PDB Entry: 4x5f, 1.7 Å

PDB Description: ecdhfr complexed with folate and nadp+ at 0.1 mpa

PDB Compounds: (B:) dihydrofolate reductase

SCOPe Domain Sequences for d4x5fb1:

Sequence; same for both SEQRES and ATOM records:

>d4x5fb1 c.71.1.0 (B:1-159) automated matches {Escherichia coli [TaxId: 83333]}
misliaalavdrvigmenampwnlpadlawfkrntlnkpvimgrhtwesigrplpgrkni
ilssqpgtddrvtwvksvdeaiaacgdvpeimvigggrvyeqflpkaqklylthidaeve
gdthfpdyepddwesvfsefhdadaqnshsycfeilerr

Timeline for d4x5fb1:

• d4x5fb1 first appeared in SCOPe 2.05, called d4x5fb_
  
• d4x5fb1 appears in SCOPe 2.07