SCOPe 2.05: Domain d5ek2a_: 5ek2 A:

Lineage for d5ek2a_ (5ek2 A:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.266: Indolic compounds 2,3-dioxygenase-like [140958] (1 superfamily)
   multihelical; bundle, contains interrupted helices

4. Superfamily a.266.1: Indolic compounds 2,3-dioxygenase-like [140959] (3 families)
   contains heme-dependent enzymes

5. Family a.266.1.2: Indoleamine 2,3-dioxygenase-like [140963] (3 proteins)
   Pfam PF01231; contains extra N-terminal all-alpha subdomain of similar fold to the GST C-terminal domain (47615)

6. Protein automated matches [190585] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187592] (7 PDB entries)

8. Domain d5ek2a_: 5ek2 A: [280015]
   automated match to d2d0tb_
   complexed with 5pj, hem

Details for d5ek2a_

PDB Entry: 5ek2, 2.68 Å

PDB Description: crystal structure of the indoleamine 2,3-dioxygenagse 1 (ido1) complexed with nlg919 analogue

PDB Compounds: (A:) Indoleamine 2,3-dioxygenase 1

SCOPe Domain Sequences for d5ek2a_:

Sequence, based on SEQRES records:

>d5ek2a_ a.266.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
skeyhideevgfalpnpqenlpdfyndwmfiakhlpdliesgqlrerveklnmlsidhlt
dhksqrlarlvlgcitmayvwgkghgdvrkvlprniavpycqlskklelppilvyadcvl
anwkkkdpnkpltyenmdvlfsfrdgdcskgfflvsllveiaaasaikviptvfkamqmq
erdtllkalleiasclekalqvfhqihdhvnpkaffsvlriylsgwkgnpqlsdglvyeg
fwedpkefaggsagqssvfqcfdvllgiqqtaggghaaqflqdmrrymppahrnflcsle
snpsvrefvlskgdaglreaydacvkalvslrsyhlqivtkyilipasqqpkenktsedp
skleakgtggtdlmnflktvrstteksllkeg

Sequence, based on observed residues (ATOM records):

>d5ek2a_ a.266.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
skeyhideevgfalpnpqenlpdfyndwmfiakhlpdliesgqlrerveklnmlsidhlt
dhksqrlarlvlgcitmayvwgkghgdvrkvlprniavpycqlskklelppilvyadcvl
anwkkkdpnkpltyenmdvlfsfrdgdcskgfflvsllveiaaasaikviptvfkamqmq
erdtllkalleiasclekalqvfhqihdhvnpkaffsvlriylsgwkgnpqlsdglvyeg
fwedpkefaggsagqssvfqcfdvllgiqqtaggghaaqflqdmrrymppahrnflcsle
snpsvrefvlskgdaglreaydacvkalvslrsyhlqivtkyilipasqqggtdlmnflk
tvrstteksllkeg

Timeline for d5ek2a_:

• d5ek2a_ is new in SCOPe 2.05-stable
  
• d5ek2a_ appears in SCOPe 2.06
  
• d5ek2a_ appears in the current release, SCOPe 2.08