SCOPe 2.08: Domain d4wx2a_: 4wx2 A:

Lineage for d4wx2a_ (4wx2 A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.2: Ribulose-phoshate binding barrel [51366] (7 families)

5. Family c.1.2.4: Tryptophan biosynthesis enzymes [51381] (4 proteins)

6. Protein Trp synthase alpha-subunit [51388] (9 species)

7. Species Salmonella typhimurium [TaxId:90371] [51389] (72 PDB entries)

8. Domain d4wx2a_: 4wx2 A: [279501]
   Other proteins in same PDB: d4wx2b_
   automated match to d1k8ya_
   complexed with edo, f6f, na, peg, plp

Details for d4wx2a_

PDB Entry: 4wx2, 1.75 Å

PDB Description: crystal structure of tryptophan synthase from salmonella typhimurium in complex with two f6f molecules in the alpha-site and one f6f molecule in the beta-site

PDB Compounds: (A:) tryptophan synthase alpha chain

SCOPe Domain Sequences for d4wx2a_:

Sequence, based on SEQRES records:

>d4wx2a_ c.1.2.4 (A:) Trp synthase alpha-subunit {Salmonella typhimurium [TaxId: 90371]}
meryenlfaqlndrregafvpfvtlgdpgieqslkiidtlidagadalelgvpfsdplad
gptiqnanlrafaagvtpaqcfemlalirekhptipigllmyanlvfnngidafyarceq
vgvdsvlvadvpveesapfrqaalrhniapificppnadddllrqvasygrgytyllsrs
gvtgaenrgalplhhlieklkeyhaapalqgfgisspeqvsaavragaagaisgsaivki
ieknlaspkqmlaelrsfvsamkaasra

Sequence, based on observed residues (ATOM records):

>d4wx2a_ c.1.2.4 (A:) Trp synthase alpha-subunit {Salmonella typhimurium [TaxId: 90371]}
meryenlfaqlndrregafvpfvtlgdpgieqslkiidtlidagadalelgvpfsdplad
gptiqnanlrafaagvtpaqcfemlalirekhptipigllmyanlvfnngidafyarceq
vgvdsvlvadvpveesapfrqaalrhniapificppnadddllrqvasygrgytyllshh
lieklkeyhaapalqgfgisspeqvsaavragaagaisgsaivkiieknlaspkqmlael
rsfvsamkaasra

Timeline for d4wx2a_:

• d4wx2a_ first appeared in SCOPe 2.05
  
• d4wx2a_ appears in SCOPe 2.07