SCOPe 2.05: Domain d4xumb_: 4xum B:

Lineage for d4xumb_ (4xum B:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (138 PDB entries)

8. Domain d4xumb_: 4xum B: [279046]
   automated match to d3tkma_
   complexed with imn

Details for d4xumb_

PDB Entry: 4xum, 2.4 Å

PDB Description: ppargamma ligand binding domain in complex with indomethacin

PDB Compounds: (B:) Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d4xumb_:

Sequence, based on SEQRES records:

>d4xumb_ a.123.1.1 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkh
itplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheii
ytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlai
fiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqiv
tehvqllqvikktetdmslhpllqeiykdly

Sequence, based on observed residues (ATOM records):

>d4xumb_ a.123.1.1 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgspfviydmnslmmgedkikfkhitpev
airifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmnkd
gvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviilsgdr
pgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqvik
ktetdmslhpllqeiykdly

Timeline for d4xumb_:

• d4xumb_ is new in SCOPe 2.05-stable
  
• d4xumb_ appears in SCOPe 2.06
  
• d4xumb_ appears in the current release, SCOPe 2.08