SCOPe 2.05: Domain d5afxb_: 5afx B:

Lineage for d5afxb_ (5afx B:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.128: Terpenoid synthases [48575] (1 superfamily)
   multihelical; core: 8 helices (C-J) are arranged in 2 parallel layers

4. Superfamily a.128.1: Terpenoid synthases [48576] (6 families)
   duplication: two metal-binding sites are related by a pseudo dyad that also relates helices C-F to helices G-J

5. Family a.128.1.0: automated matches [196408] (1 protein)
   not a true family

6. Protein automated matches [196409] (30 species)
   not a true protein

7. Species Trypanosome (Trypanosoma brucei) [TaxId:5691] [230726] (15 PDB entries)

8. Domain d5afxb_: 5afx B: [278534]
   automated match to d2ogda_
   complexed with mg, pvz

Details for d5afxb_

PDB Entry: 5afx, 2.39 Å

PDB Description: t. brucei farnesyl diphosphate synthase complexed with bisphosphonate bph-1238

PDB Compounds: (B:) farnesyl pyrophosphate synthase

SCOPe Domain Sequences for d5afxb_:

Sequence, based on SEQRES records:

>d5afxb_ a.128.1.0 (B:) automated matches {Trypanosome (Trypanosoma brucei) [TaxId: 5691]}
mpmqmfmqvydeiqmflleelelkfdmdpnrvrylrkmmdttclggkynrgltvidvaes
llslspnnngeeddgarrkrvlhdacvcgwmieflqahylveddimdnsvtrrgkpcwyr
hpdvtvqcaindglllkswthmmamhffadrpflqdllcrfnrvdyttavgqlydvtsmf
dsnkldpdvsqptttdfaeftlsnykrivkyktayytyllplvmglivsealptvdmgvt
eelamlmgeyfqvqddvmdcftpperlgkvgtdiqdakcswlavtflakassaqvaefka
nygsgdsekvatvrrlyeeadlqgdyvayeaavaeqvkelieklrlcspgfaasvetlwg
ktykrqk

Sequence, based on observed residues (ATOM records):

>d5afxb_ a.128.1.0 (B:) automated matches {Trypanosome (Trypanosoma brucei) [TaxId: 5691]}
mpmqmfmqvydeiqmflleelelkfdmdpnrvrylrkmmdttclggkynrgltvidvaes
llsdgarrkrvlhdacvcgwmieflqahylveddimdnsvtrrgkpcwyrhpdvtvqcai
ndglllkswthmmamhffadrpflqdllcrfnrvdyttavgqlydvtsmfdsnkldpdvs
qptttdfaeftlsnykrivkyktayytyllplvmglivsealptvdmgvteelamlmgey
fqvqddvmdcftpperlgkvgtdiqdakcswlavtflakassaqvaefkanygsgdsekv
atvrrlyeeadlqgdyvayeaavaeqvkelieklrlcspgfaasvetlwgktykrqk

Timeline for d5afxb_:

• d5afxb_ is new in SCOPe 2.05-stable
  
• d5afxb_ appears in SCOPe 2.06
  
• d5afxb_ appears in the current release, SCOPe 2.08