SCOPe 2.05: Domain d5acyb_: 5acy B:

Lineage for d5acyb_ (5acy B:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.29: Bromodomain-like [47363] (15 superfamilies)
   4 helices; bundle; minor mirror variant of up-and-down topology

4. Superfamily a.29.2: Bromodomain [47370] (2 families)

5. Family a.29.2.0: automated matches [191428] (1 protein)
   not a true family

6. Protein automated matches [190615] (7 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187641] (258 PDB entries)

8. Domain d5acyb_: 5acy B: [277798]
   automated match to d3u5la_
   complexed with 9s3, edo

Details for d5acyb_

PDB Entry: 5acy, 2.01 Å

PDB Description: n-terminal bromodomain of human brd4 with 1-(2r,4s)-2- methyl-4-(phenylamino)-6-4-(piperidin-1-ylmethyl)phenyl- 1,2,3,4-tetrahydroquinolin-1-yl-ethan-1-one

PDB Compounds: (B:) Bromodomain-containing protein 4

SCOPe Domain Sequences for d5acyb_:

Sequence; same for both SEQRES and ATOM records:

>d5acyb_ a.29.2.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
nelptee

Timeline for d5acyb_:

• d5acyb_ is new in SCOPe 2.05-stable
  
• d5acyb_ is called d5acyb1 in SCOPe 2.06
  
• d5acyb_ appears in the current release, SCOPe 2.08, called d5acyb1