SCOPe 2.08: Domain d4whfa_: 4whf A:

Lineage for d4whfa_ (4whf A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Orphan nuclear receptor NR4A1 [158811] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [158812] (15 PDB entries)
   Uniprot P22736 363-595

8. Domain d4whfa_: 4whf A: [276771]
   automated match to d3v3qa1
   complexed with 3mx, gol

Details for d4whfa_

PDB Entry: 4whf, 2.27 Å

PDB Description: crystal structure of tr3 lbd in complex with 1-(3,4,5- trihydroxyphenyl)decan-1-one

PDB Compounds: (A:) Nuclear receptor subfamily 4 group A member 1

SCOPe Domain Sequences for d4whfa_:

Sequence, based on SEQRES records:

>d4whfa_ a.123.1.1 (A:) Orphan nuclear receptor NR4A1 {Human (Homo sapiens) [TaxId: 9606]}
anlltslvrahldsgpstakldyskfqelvlphfgkedagdvqqfydllsgslevirkwa
ekipgfaelspadqdlllesaflelfilrlayrskpgegklifcsglvlhrlqcargfgd
widsilafsrslhsllvdvpafaclsalvlitdrhglqeprrveelqnriasclkehvaa
vagepqpasclsrllgklpelrtlctqglqrifylkledlvppppiidkifmdtlpf

Sequence, based on observed residues (ATOM records):

>d4whfa_ a.123.1.1 (A:) Orphan nuclear receptor NR4A1 {Human (Homo sapiens) [TaxId: 9606]}
anlltslvrahldsgpstakldyskfqelvlphfgkedagdvqqfydllsgslevirkwa
ekipgfaelspadqdlllesaflelfilrlayrskpgegklifcsglvlhrlqcargfgd
widsilafsrslhsllvdvpafaclsalvlitdrhglqeprrveelqnriasclkehvaa
vagclsrllgklpelrtlctqglqrifylkledlvppppiidkifmdtlpf

Timeline for d4whfa_:

• d4whfa_ first appeared in SCOPe 2.05
  
• d4whfa_ appears in SCOPe 2.07