SCOPe 2.08: Domain d4w63a_: 4w63 A:

Lineage for d4w63a_ (4w63 A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (43 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.1: Acetylcholinesterase-like [53475] (6 proteins)
   automatically mapped to Pfam PF00135

6. Protein Acetylcholinesterase [53476] (6 species)

7. Species Pacific electric ray (Torpedo californica) [TaxId:7787] [53477] (98 PDB entries)
   Uniprot P04058 25-556

8. Domain d4w63a_: 4w63 A: [276751]
   automated match to d2dfpa_
   complexed with htb, nag

Details for d4w63a_

PDB Entry: 4w63, 2.8 Å

PDB Description: torpedo californica acetylcholinesterase in complex with a tacrine- benzofuran hybrid inhibitor

PDB Compounds: (A:) acetylcholinesterase

SCOPe Domain Sequences for d4w63a_:

Sequence; same for both SEQRES and ATOM records:

>d4w63a_ c.69.1.1 (A:) Acetylcholinesterase {Pacific electric ray (Torpedo californica) [TaxId: 7787]}
dhsellvntksgkvmgtrvpvlsshisaflgipfaeppvgnmrfrrpepkkpwsgvwnas
typnncqqyvdeqfpgfsgsemwnpnremsedclylniwvpsprpksttvmvwiygggfy
sgsstldvyngkylayteevvlvslsyrvgafgflalhgsqeapgnvglldqrmalqwvh
dniqffggdpktvtifgesaggasvgmhilspgsrdlfrrailqsgspncpwasvsvaeg
rrravelgrnlncnlnsdeelihclrekkpqelidvewnvlpfdsifrfsfvpvidgeff
ptslesmlnsgnfkktqillgvnkdegsffllygapgfskdseskisredfmsgvklsvp
handlgldavtlqytdwmddnngiknrdglddivgdhnvicplmhfvnkytkfgngtyly
ffnhrasnlvwpewmgvihgyeiefvfglplvkelnytaeeealsrrimhywatfaktgn
pnephsqeskwplfttkeqkfidlntepmkvhqrlrvqmcvfwnqflpkllnat

Timeline for d4w63a_:

• d4w63a_ first appeared in SCOPe 2.05
  
• d4w63a_ appears in SCOPe 2.07