Lineage for d5bvea_ (5bve A:)

  1. Root: SCOPe 2.05
  2. 1886641Class d: Alpha and beta proteins (a+b) [53931] (381 folds)
  3. 1929110Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1929111Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1929232Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1930838Protein MAP kinase Erk2 [56134] (2 species)
    CMGC group; ERK/MAPK subfamily; serine/threonine kinase
  7. 1930839Species Human (Homo sapiens) [TaxId:9606] [56135] (13 PDB entries)
  8. 1930852Domain d5bvea_: 5bve A: [276654]
    automated match to d1erka_
    complexed with 4vg, so4

Details for d5bvea_

PDB Entry: 5bve (more details), 2 Å

PDB Description: tetrahydropyrrolo-diazepenones as inhibitors of erk2 kinase
PDB Compounds: (A:) Mitogen-activated protein kinase 1

SCOPe Domain Sequences for d5bvea_:

Sequence, based on SEQRES records: (download)

>d5bvea_ d.144.1.7 (A:) MAP kinase Erk2 {Human (Homo sapiens) [TaxId: 9606]}
agpemvrgqvfdvgprytnlsyigegaygmvcsaydnvnkvrvaikkispfehqtycqrt
lreikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqhlsndhicy
flyqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadpdhdhtgflteyv
atrwyrapeimlnskgytksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgsps
qedlnciinlkarnyllslphknkvpwnrlfpnadskaldlldkmltfnphkrieveqal
ahpyleqyydpsdepiaeapfkfdmelddlpkeklkelifeetarfqpgy

Sequence, based on observed residues (ATOM records): (download)

>d5bvea_ d.144.1.7 (A:) MAP kinase Erk2 {Human (Homo sapiens) [TaxId: 9606]}
agpemvrgqvfdvgprytnlsyigegaygmvcsaydnvnkvrvaikkispfehqtycqrt
lreikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqhlsndhicy
flyqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvtrwyrapeimlntks
idiwsvgcilaemlsnrpifpgkhyldqlnhilgilgspsqedlnciinlkarnyllslp
hknkvpwnrlfpnadskaldlldkmltfnphkrieveqalahpyleqyydpsdepiaeap
fkfdmelddlpkeklkelifeetarfqpgy

SCOPe Domain Coordinates for d5bvea_:

Click to download the PDB-style file with coordinates for d5bvea_.
(The format of our PDB-style files is described here.)

Timeline for d5bvea_: