Lineage for d4zzxa2 (4zzx A:365-583)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2558127Fold d.166: ADP-ribosylation [56398] (1 superfamily)
    unusual fold
  4. 2558128Superfamily d.166.1: ADP-ribosylation [56399] (8 families) (S)
  5. 2558349Family d.166.1.2: Poly(ADP-ribose) polymerase, C-terminal domain [56416] (2 proteins)
    automatically mapped to Pfam PF00644
  6. 2558373Protein automated matches [227023] (1 species)
    not a true protein
  7. 2558374Species Human (Homo sapiens) [TaxId:9606] [225783] (6 PDB entries)
  8. 2558379Domain d4zzxa2: 4zzx A:365-583 [276100]
    Other proteins in same PDB: d4zzxa1, d4zzxb1
    automated match to d1gs0a2
    complexed with fsu

Details for d4zzxa2

PDB Entry: 4zzx (more details), 1.65 Å

PDB Description: structure of parp2 catalytic domain bound to an isoindolinone inhibitor
PDB Compounds: (A:) Poly [ADP-ribose] polymerase 2

SCOPe Domain Sequences for d4zzxa2:

Sequence, based on SEQRES records: (download)

>d4zzxa2 d.166.1.2 (A:365-583) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lhcalrpldhesyefkvisqylqsthapthsdytmtlldlfevekdgekeafredlhnrm
llwhgsrmsnwvgilshglriappeapitgymfgkgiyfadmssksanycfasrlkntgl
lllsevalgqcnelleanpkaegllqgkhstkglgkmapssahfvtlngstvplgpasdt
gilnpdgytlnyneyivynpnqvrmryllkvqfnflqlw

Sequence, based on observed residues (ATOM records): (download)

>d4zzxa2 d.166.1.2 (A:365-583) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lhcalrpldhesyefkvisqylqsthapthsdytmtlldlfevekdgekeafredlhnrm
llwhgsrmsnwvgilshglriappeapitgymfgkgiyfadmssksanycfasrlkntgl
lllsevalgqcnelleanpkaegllqgkhstkglgkmapssahfvtlngstvplgpasdt
gilngytlnyneyivynpnqvrmryllkvqfnflqlw

SCOPe Domain Coordinates for d4zzxa2:

Click to download the PDB-style file with coordinates for d4zzxa2.
(The format of our PDB-style files is described here.)

Timeline for d4zzxa2:

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Domains from same chain:
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d4zzxa1