SCOPe 2.08: Domain d5bvka1: 5bvk A:604-905

Lineage for d5bvka1 (5bvk A:604-905)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (37 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1476 PDB entries)

8. Domain d5bvka1: 5bvk A:604-905 [275585]
   Other proteins in same PDB: d5bvka2
   automated match to d3zosb_
   complexed with 4vc, iod

Details for d5bvka1

PDB Entry: 5bvk, 2.29 Å

PDB Description: fragment-based discovery of potent and selective ddr1/2 inhibitors

PDB Compounds: (A:) epithelial discoidin domain-containing receptor 1

SCOPe Domain Sequences for d5bvka1:

Sequence, based on SEQRES records:

>d5bvka1 d.144.1.0 (A:604-905) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dfprsrlrfkeklgegqfgevhlcevdspqdlvsldfplnvrkghpllvavkilrpdatk
narndflkevkimsrlkdpniirllgvcvqddplcmitdymengdlnqflsahqledkaa
egapgdgqaaqgptisypmllhvaaqiasgmrylatlnfvhrdlatrnclvgenftikia
dfgmsrnlyagdyyrvqgravlpirwmawecilmgkfttasdvwafgvtlwevlmlcraq
pfgqltdeqvienageffrdqgrqvylsrppacpqglyelmlrcwsreseqrppfsqlhr
fl

Sequence, based on observed residues (ATOM records):

>d5bvka1 d.144.1.0 (A:604-905) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dfprsrlrfkeklgegqfgevhlcevdshpllvavkilrpdatknarndflkevkimsrl
kdpniirllgvcvqddplcmitdymengdlnqflsahqledkptisypmllhvaaqiasg
mrylatlnfvhrdlatrnclvgenftikiadfgmsrnlyagdyyrvqgravlpirwmawe
cilmgkfttasdvwafgvtlwevlmlcraqpfgqltdeqvienageffrdqgrqvylsrp
pacpqglyelmlrcwsreseqrppfsqlhrfl

Timeline for d5bvka1:

• d5bvka1 first appeared in SCOPe 2.05, called d5bvka_
  
• d5bvka1 was called d5bvka_ in SCOPe 2.07