Lineage for d5a4ca_ (5a4c A:)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2542179Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2542180Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2542316Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2543630Protein Fibroblast growth factor receptor 1 [56158] (1 species)
    PTK group; FGFR subfamily; membrane spanning protein tyrosine kinase
  7. 2543631Species Human (Homo sapiens) [TaxId:9606] [56159] (47 PDB entries)
  8. 2543668Domain d5a4ca_: 5a4c A: [275544]
    Other proteins in same PDB: d5a4cb2
    automated match to d4v04b_
    complexed with edo, so4, xoj

Details for d5a4ca_

PDB Entry: 5a4c (more details), 2.09 Å

PDB Description: fgfr1 ligand complex
PDB Compounds: (A:) fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, pfeiffer syndrome), isoform cra_b

SCOPe Domain Sequences for d5a4ca_:

Sequence, based on SEQRES records: (download)

>d5a4ca_ d.144.1.7 (A:) Fibroblast growth factor receptor 1 {Human (Homo sapiens) [TaxId: 9606]}
elpedprwelprdrlvlgkplgegafgqvvlaeaigldkdkpnrvtkvavkmlksdatek
dlsdlisememmkmigkhkniinllgactqdgplyviveyaskgnlreylqarrppgley
synpshnpeeqlsskdlvscayqvargmeylaskkcihrdlaarnvlvtednvmkiadfg
lardihhidyykkttngrlpvkwmapealfdriythqsdvwsfgvllweiftlggspypg
vpveelfkllkeghrmdkpsnctnelymmmrdcwhavpsqrptfkqlvedldrivaltsn
qe

Sequence, based on observed residues (ATOM records): (download)

>d5a4ca_ d.144.1.7 (A:) Fibroblast growth factor receptor 1 {Human (Homo sapiens) [TaxId: 9606]}
elpedprwelprdrlvlgkplgefgqvvlaeaigldkdkpnrvtkvavkmlksdatekdl
sdlisememmkmigkhkniinllgactqdgplyviveyaskgnlreylqarrppgleysy
npshnpeeqlsskdlvscayqvargmeylaskkcihrdlaarnvlvtednvmkiadfgli
dyykkttngrlpvkwmapealfdriythqsdvwsfgvllweiftlggspypgvpveelfk
llkeghrmdkpsnctnelymmmrdcwhavpsqrptfkqlvedldrivaltsnqe

SCOPe Domain Coordinates for d5a4ca_:

Click to download the PDB-style file with coordinates for d5a4ca_.
(The format of our PDB-style files is described here.)

Timeline for d5a4ca_: