Lineage for d4zxyh_ (4zxy H:)

  1. Root: SCOPe 2.08
  2. 2739516Class b: All beta proteins [48724] (180 folds)
  3. 2794584Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 2794585Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 2794859Family b.47.1.2: Eukaryotic proteases [50514] (49 proteins)
  6. 2795114Protein Coagulation factor VIIa [50550] (1 species)
  7. 2795115Species Human (Homo sapiens) [TaxId:9606] [50551] (90 PDB entries)
    Uniprot P08709 213-466 ! Uniprot P08709 213-446
  8. 2795175Domain d4zxyh_: 4zxy H: [275321]
    Other proteins in same PDB: d4zxyl_
    automated match to d1klih_
    complexed with 4t1, ca, gol, so4

Details for d4zxyh_

PDB Entry: 4zxy (more details), 2.06 Å

PDB Description: factor viia in complex with the inhibitor (2r)-2-[(1-aminoisoquinolin- 6-yl)amino]-4,11-diazatricyclo[14.2.2.1~6,10~]henicosa-1(18),6(21),7, 9,16,19-hexaene-3,12-dione
PDB Compounds: (H:) Coagulation factor VIIA heavy chain

SCOPe Domain Sequences for d4zxyh_:

Sequence, based on SEQRES records: (download)

>d4zxyh_ b.47.1.2 (H:) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
seprpgvllrapfp

Sequence, based on observed residues (ATOM records): (download)

>d4zxyh_ b.47.1.2 (H:) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrspniteymfcagysdgs
kdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmrsepr
pgvllrapfp

SCOPe Domain Coordinates for d4zxyh_:

Click to download the PDB-style file with coordinates for d4zxyh_.
(The format of our PDB-style files is described here.)

Timeline for d4zxyh_: