SCOPe 2.06: Domain d4xiib_: 4xii B:

Lineage for d4xiib_ (4xii B:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (42 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.0: automated matches [191404] (1 protein)
   not a true family

6. Protein automated matches [190543] (91 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188340] (73 PDB entries)

8. Domain d4xiib_: 4xii B: [274809]
   automated match to d2x8ba_
   complexed with 40v, cl, edo, fuc, ful, nag

Details for d4xiib_

PDB Entry: 4xii, 2.7 Å

PDB Description: x-ray structure of human butyrylcholinesterase in complex with n-((1- (2,3-dihydro-1h-inden-2-yl)piperidin-3-yl)methyl)-8-hydroxy-n-(2- methoxyethyl)-5-nitroquinoline-7-carboxamide

PDB Compounds: (B:) cholinesterase

SCOPe Domain Sequences for d4xiib_:

Sequence, based on SEQRES records:

>d4xiib_ c.69.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
iiiatkngkvrgmnltvfggtvtaflgipyaqpplgrlrfkkpqsltkwsdiwnatkyan
sccqnidqsfpgfhgsemwnpntdlsedclylnvwipapkpknatvliwiygggfqtgts
slhvydgkflarvervivvsmnyrvgalgflalpgnpeapgnmglfdqqlalqwvqknia
afggnpksvtlfgesagaasvslhllspgshslftrailqsgsfnapwavtslyearnrt
lnlakltgcsreneteiikclrnkdpqeillneafvvpygtplsvnfgptvdgdfltdmp
dillelgqfkktqilvgvnkdegtaflvygapgfskdnnsiitrkefqeglkiffpgvse
fgkesilfhytdwvddqrpenyrealgdvvgdynficpaleftkkfsewgnnaffyyfeh
rssklpwpewmgvmhgyeiefvfglplerrdnytkaeeilsrsivkrwanfakygnpnet
qnnstswpvfksteqkyltlntestrimtklraqqcrfwtsffpkvl

Sequence, based on observed residues (ATOM records):

>d4xiib_ c.69.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
iiiatkngkvrgmnltvfggtvtaflgipyaqpplgrlrfkkpqsltkwsdiwnatkyan
sccqnidqsfpgfhgsemwnpntdlsedclylnvwipapkpknatvliwiygggfqtgts
slhvydgkflarvervivvsmnyrvgalgflalpgnpeapgnmglfdqqlalqwvqknia
afggnpksvtlfgesagaasvslhllspgshslftrailqsgsfnapwavtslyearnrt
lnlakltgcsreneteiikclrnkdpqeillneafvvpygtplsvnfgptvdgdfltdmp
dillelgqfkktqilvgvnkdegtaflvygapgfskdnnsiitrkefqeglkiffpgvse
fgkesilfhytdwvddqrpenyrealgdvvgdynficpaleftkkfsewgnnaffyyfeh
rssklpwpewmgvmhgyeiefvfglplerrdnytkaeeilsrsivkrwanfakygnpnet
nstswpvfksteqkyltlntestrimtklraqqcrfwtsffpkvl

Timeline for d4xiib_:

• d4xiib_ first appeared in SCOPe 2.05
  
• d4xiib_ appears in SCOPe 2.07
  
• d4xiib_ appears in the current release, SCOPe 2.08