Lineage for d4ui0a_ (4ui0 A:)

  1. Root: SCOPe 2.05
  2. 1959977Class g: Small proteins [56992] (92 folds)
  3. 1963384Fold g.17: Cystine-knot cytokines [57500] (1 superfamily)
    disulfide-rich fold; common core is all-beta
  4. 1963385Superfamily g.17.1: Cystine-knot cytokines [57501] (8 families) (S)
  5. 1963472Family g.17.1.2: Transforming growth factor (TGF)-beta [57507] (8 proteins)
  6. 1963492Protein Bone morphogenetic protein-2 (BMP-2) [57516] (1 species)
  7. 1963493Species Human (Homo sapiens) [TaxId:9606] [57517] (13 PDB entries)
  8. 1963513Domain d4ui0a_: 4ui0 A: [272410]
    automated match to d3bmpa_
    complexed with cl, flc, mpd

Details for d4ui0a_

PDB Entry: 4ui0 (more details), 2.8 Å

PDB Description: crystal structure of the human rgmb-bmp2 complex, crystal form 2
PDB Compounds: (A:) Bone morphogenetic protein 2

SCOPe Domain Sequences for d4ui0a_:

Sequence, based on SEQRES records: (download)

>d4ui0a_ g.17.1.2 (A:) Bone morphogenetic protein-2 (BMP-2) {Human (Homo sapiens) [TaxId: 9606]}
kssckrhplyvdfsdvgwndwivappgyhafychgecpfpladhlnstnhaivqtlvnsv
nskipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr

Sequence, based on observed residues (ATOM records): (download)

>d4ui0a_ g.17.1.2 (A:) Bone morphogenetic protein-2 (BMP-2) {Human (Homo sapiens) [TaxId: 9606]}
kssckrhplyvdfsdvgwndwivappgyhafychgecpfphlnstnhaivqtlvnsvnsk
ipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr

SCOPe Domain Coordinates for d4ui0a_:

Click to download the PDB-style file with coordinates for d4ui0a_.
(The format of our PDB-style files is described here.)

Timeline for d4ui0a_: