SCOPe 2.08: Domain d4ui1b_: 4ui1 B:

Lineage for d4ui1b_ (4ui1 B:)

1. Root: SCOPe 2.08

2. Class g: Small proteins [56992] (100 folds)

3. Fold g.17: Cystine-knot cytokines [57500] (1 superfamily)
   disulfide-rich fold; common core is all-beta

4. Superfamily g.17.1: Cystine-knot cytokines [57501] (8 families)

5. Family g.17.1.2: Transforming growth factor (TGF)-beta [57507] (8 proteins)

6. Protein Bone morphogenetic protein-2 (BMP-2) [57516] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [57517] (16 PDB entries)

8. Domain d4ui1b_: 4ui1 B: [272406]
   automated match to d3bmpa_
   complexed with cl, edo, no3

Details for d4ui1b_

PDB Entry: 4ui1, 2.35 Å

PDB Description: crystal structure of the human rgmc-bmp2 complex

PDB Compounds: (B:) Bone morphogenetic protein 2

SCOPe Domain Sequences for d4ui1b_:

Sequence; same for both SEQRES and ATOM records:

>d4ui1b_ g.17.1.2 (B:) Bone morphogenetic protein-2 (BMP-2) {Human (Homo sapiens) [TaxId: 9606]}
lkssckrhplyvdfsdvgwndwivappgyhafychgecpfpladhlnstnhaivqtlvns
vnskipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr

Timeline for d4ui1b_:

• d4ui1b_ first appeared in SCOPe 2.05
  
• d4ui1b_ appears in SCOPe 2.07