Lineage for d3wyxa_ (3wyx A:)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2218047Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2218048Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2222093Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. 2222094Protein automated matches [190417] (25 species)
    not a true protein
  7. 2222237Species Human (Homo sapiens) [TaxId:9606] [187294] (882 PDB entries)
  8. 2223514Domain d3wyxa_: 3wyx A: [271329]
    automated match to d3dbqa_
    complexed with iod, o38

Details for d3wyxa_

PDB Entry: 3wyx (more details), 2.9 Å

PDB Description: crystal structure of human mps1 catalytic domain in complex with 6- ((3-(cyanomethoxy)-4-(1-methyl-1h-pyrazol-4-yl)phenyl)amino)-2- (cyclohexylamino)nicotinonitrile
PDB Compounds: (A:) Dual specificity protein kinase TTK

SCOPe Domain Sequences for d3wyxa_:

Sequence, based on SEQRES records: (download)

>d3wyxa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ecisvkgriysilkqigsggsskvfqvlnekkqiyaikyvnleeadnqtldsyrneiayl
nklqqhsdkiirlydyeitdqyiymvmecgnidlnswlkkkksidpwerksywknmleav
htihqhgivhsdlkpanflivdgmlklidfgianqmqpdttsvvkdsqvgtvnymppeai
kdmsssrengkskskispksdvwslgcilyymtygktpfqqiinqisklhaiidpnheie
fpdipekdlqdvlkcclkrdpkqrisipellahpyvqiqt

Sequence, based on observed residues (ATOM records): (download)

>d3wyxa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ecisvkgriysilkqigsggsskvfqvlnekkqiyaikyvnleeadnqtldsyrneiayl
nklqqhsdkiirlydyeitdqyiymvmecgnidlnswlkkkksidpwerksywknmleav
htihqhgivhsdlkpanflivdgmlklidfgianqmqpgtvnymppeaikdmsispksdv
wslgcilyymtygktpfqqiinqisklhaiidpnheiefpdipekdlqdvlkcclkrdpk
qrisipellahpyvqiqt

SCOPe Domain Coordinates for d3wyxa_:

Click to download the PDB-style file with coordinates for d3wyxa_.
(The format of our PDB-style files is described here.)

Timeline for d3wyxa_: