SCOPe 2.08: Domain d4xeya_: 4xey A:

Lineage for d4xeya_ (4xey A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (850 PDB entries)

8. Domain d4xeya_: 4xey A: [271088]
   Other proteins in same PDB: d4xeyb1
   automated match to d2f4ja_
   complexed with 1n1

Details for d4xeya_

PDB Entry: 4xey, 2.89 Å

PDB Description: crystal structure of an sh2-kinase domain construct of c-abl tyrosine kinase

PDB Compounds: (A:) Tyrosine-protein kinase ABL1

SCOPe Domain Sequences for d4xeya_:

Sequence, based on SEQRES records:

>d4xeya_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
nydkwemertditmkhklgggqygevyegvwkkysltvavktlkedtmeveeflkeaavm
keikhpnlvqllgvctreppfyiitefmtygnlldylrecnrqevnavvllymatqissa
meylekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpikwtapes
laynkfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpegcpekvye
lmracwqwnpsdrpsfaeihqafetmfqessis

Sequence, based on observed residues (ATOM records):

>d4xeya_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
nydkwemertditmkhklggevyegvwkkysltvavktlkedtmeveeflkeaavmkeik
hpnlvqllgvctreppfyiitefmtygnlldylrecnrqevnavvllymatqissameyl
ekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpikwtapeslayn
kfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpegcpekvyelmra
cwqwnpsdrpsfaeihqafetmfqessis

Timeline for d4xeya_:

• d4xeya_ first appeared in SCOPe 2.05
  
• d4xeya_ appears in SCOPe 2.07