Lineage for d5am7b_ (5am7 B:)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2218047Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2218048Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2218179Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2219468Protein Fibroblast growth factor receptor 1 [56158] (1 species)
    PTK group; FGFR subfamily; membrane spanning protein tyrosine kinase
  7. 2219469Species Human (Homo sapiens) [TaxId:9606] [56159] (32 PDB entries)
  8. 2219501Domain d5am7b_: 5am7 B: [270207]
    automated match to d4v04b_
    complexed with 38o, cl; mutant

Details for d5am7b_

PDB Entry: 5am7 (more details), 1.96 Å

PDB Description: fgfr1 mutant with an inhibitor
PDB Compounds: (B:) fibroblast growth factor receptor 1

SCOPe Domain Sequences for d5am7b_:

Sequence, based on SEQRES records: (download)

>d5am7b_ d.144.1.7 (B:) Fibroblast growth factor receptor 1 {Human (Homo sapiens) [TaxId: 9606]}
agvseyelpedprwelprdrlvlgkplgegafgqvvlaeaigldkdkpnrvtkvavkmlk
sdatekdlsdlisememmkmigkhkniinllgactqdgplyvimeyaskgnlreylqarr
ppgleysynpshnpeeqlsskdlvscayqvargmeylaskkcihrdlaarnvlvtednvm
kiadfglardihhidyykkttngrlpvkwmapealfdriythqsdvwsfgvllweiftlg
gspypgvpveelfkllkeghrmdkpsnctnelymmmrdcwhavpsqrptfkqlvedldri
valts

Sequence, based on observed residues (ATOM records): (download)

>d5am7b_ d.144.1.7 (B:) Fibroblast growth factor receptor 1 {Human (Homo sapiens) [TaxId: 9606]}
agvseyelpedprwelprdrlvlgkplgegqvvlaeaigldkdkpnrvtkvavkmlksda
tekdlsdlisememmkmigkhkniinllgactqdgplyvimeyaskgnlreylqarrppg
peeqlsskdlvscayqvargmeylaskkcihrdlaarnvlvtednvmkiadfglardyyk
kttngrlpvkwmapealfdriythqsdvwsfgvllweiftlggspypgvpveelfkllke
ghrmdkpsnctnelymmmrdcwhavpsqrptfkqlvedldrivalts

SCOPe Domain Coordinates for d5am7b_:

Click to download the PDB-style file with coordinates for d5am7b_.
(The format of our PDB-style files is described here.)

Timeline for d5am7b_: