SCOPe 2.08: Domain d4urxs_: 4urx S:

Lineage for d4urxs_ (4urx S:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.117: Ras GEF [48365] (1 superfamily)
   multihelical

4. Superfamily a.117.1: Ras GEF [48366] (1 family)

5. Family a.117.1.1: Ras GEF [48367] (2 proteins)

6. Protein automated matches [269917] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [269918] (10 PDB entries)

8. Domain d4urxs_: 4urx S: [269919]
   Other proteins in same PDB: d4urxr1, d4urxr2
   automated match to d1nvus_
   complexed with fk1, fmt, hxy

Details for d4urxs_

PDB Entry: 4urx, 2.49 Å

PDB Description: the crystal structure of h-ras and sos in complex with ligands

PDB Compounds: (S:) Son of sevenless homolog 1

SCOPe Domain Sequences for d4urxs_:

Sequence, based on SEQRES records:

>d4urxs_ a.117.1.1 (S:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qmrlpsadvyrfaepdseeniifeenmqpkagipiikagtviklierltyhmyadpnfvr
tflttyrsfckpqellsliierfeipepepteadriaiengdqplsaelkrfrkeyiqpv
qlrvlnvcrhwvehhfydferdayllqrmeefigtvrgkamkkwvesitkiiqrkkiard
ngpghnitfqsspptvewhisrpghietfdlltlhpieiarqltllesdlyravqpselv
gsvwtkedkeinspnllkmirhttnltlwfekcivetenleervavvsriieilqvfqel
nnfngvlevvsamnsspvyrldhtfeqipsrqkkileeahelsedhykkylaklrsinpp
cvpffgiyltnilkteegnpevlkrhgkelinfskrrkvaeitgeiqqyqnqpyclrves
dikrffenlnpmgnsmekeftdylfnksleieprnpkplprfpkkysyplkspgvrpsnp

Sequence, based on observed residues (ATOM records):

>d4urxs_ a.117.1.1 (S:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qmrlpsadvyrfaepdseeniifeenmqpkagipiikagtviklierltyhmyadpnfvr
tflttyrsfckpqellsliierfeipepelsaelkrfrkeyiqpvqlrvlnvcrhwvehh
fydferdayllqrmeefigtvrgkamkkwvesitkiiqrkkiasspptvewhisrpghie
tfdlltlhpieiarqltllesdlyravqpselvgsvwtkedkeinspnllkmirhttnlt
lwfekcivetenleervavvsriieilqvfqelnnfngvlevvsamnsspvyrldhtfeq
ipsrqkkileeahelsedhykkylaklrsinppcvpffgiyltnilkteegnpevlkrhg
kelinfskrrkvaeitgeiqqyqnqpyclrvesdikrffenlnpmgnsmekeftdylfnk
sleieprnpkplprfpkkysyplkspgvrpsnp

Timeline for d4urxs_:

• d4urxs_ first appeared in SCOPe 2.05
  
• d4urxs_ appears in SCOPe 2.07