Lineage for d4xi2a2 (4xi2 A:384-657)

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2979545Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2979546Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2984752Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. 2984753Protein automated matches [190417] (37 species)
    not a true protein
  7. 2987271Species Mouse (Mus musculus) [TaxId:10090] [194605] (31 PDB entries)
  8. 2987302Domain d4xi2a2: 4xi2 A:384-657 [269603]
    Other proteins in same PDB: d4xi2a1
    automated match to d2ptka3
    complexed with au

Details for d4xi2a2

PDB Entry: 4xi2 (more details), 2.6 Å

PDB Description: crystal structure of an auto-inhibited form of bruton's tryrosine kinase
PDB Compounds: (A:) Tyrosine-protein kinase BTK

SCOPe Domain Sequences for d4xi2a2:

Sequence; same for both SEQRES and ATOM records: (download)

>d4xi2a2 d.144.1.0 (A:384-657) automated matches {Mouse (Mus musculus) [TaxId: 10090]}
apstaglgygsweidpkdltflkelgtgqfgvvkygkwrgqydvaikmiregsmsedefi
eeakvmmnlsheklvqlygvctkqrpifiiteymangcllnylremrhrfqtqqllemck
dvceameyleskqflhrdlaarnclvndqgvvkvsdfglsryvlddeytssvgskfpvrw
sppevlmyskfssksdiwafgvlmweiyslgkmpyerftnsetaehiaqglrlyrphlas
ervytimyscwhekaderpsfkillsnildvmde

SCOPe Domain Coordinates for d4xi2a2:

Click to download the PDB-style file with coordinates for d4xi2a2.
(The format of our PDB-style files is described here.)

Timeline for d4xi2a2:

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Domains from same chain:
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d4xi2a1