SCOPe 2.08: Domain d4xh9e_: 4xh9 E:

Lineage for d4xh9e_ (4xh9 E:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (81 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein RhoA [52612] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52613] (39 PDB entries)
   Uniprot P61586 2-181

8. Domain d4xh9e_: 4xh9 E: [269220]
   automated match to d3lw8d_

Details for d4xh9e_

PDB Entry: 4xh9, 2 Å

PDB Description: crystal structure of human rhoa in complex with dh/ph fragment of the guanine nucleotide exchange factor net1

PDB Compounds: (E:) transforming protein rhoa

SCOPe Domain Sequences for d4xh9e_:

Sequence, based on SEQRES records:

>d4xh9e_ c.37.1.8 (E:) RhoA {Human (Homo sapiens) [TaxId: 9606]}
airkklvivgdgacgktcllivnskdqfpevyvptvfenyvadievdgkqvelalwdtag
qedydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvgnkkdlr
ndehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematraalq

Sequence, based on observed residues (ATOM records):

>d4xh9e_ c.37.1.8 (E:) RhoA {Human (Homo sapiens) [TaxId: 9606]}
airkklvivgdgacgktcllivnspevyvptvfenyvadievdgkqvelalwdtagqedy
drlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvgnkkdlrndeh
trrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematraalq

Timeline for d4xh9e_:

• d4xh9e_ first appeared in SCOPe 2.05
  
• d4xh9e_ appears in SCOPe 2.07