SCOPe 2.06: Domain d4x0ua_: 4x0u A:

Lineage for d4x0ua_ (4x0u A:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.82: ALDH-like [53719] (1 superfamily)
   consists of two similar domains with 3 layers (a/b/a) each; duplication
   core: parallel beta-sheet of 5 strands, order 32145

4. Superfamily c.82.1: ALDH-like [53720] (3 families)
   binds NAD differently from other NAD(P)-dependent oxidoreductases

5. Family c.82.1.0: automated matches [191448] (1 protein)
   not a true family

6. Protein automated matches [190683] (49 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [225691] (17 PDB entries)

8. Domain d4x0ua_: 4x0u A: [269145]
   automated match to d2jg7a_
   complexed with 3w9, mg

Details for d4x0ua_

PDB Entry: 4x0u, 1.95 Å

PDB Description: structure aldh7a1 inactivated by 4-diethylaminobenzaldehyde

PDB Compounds: (A:) Alpha-aminoadipic semialdehyde dehydrogenase

SCOPe Domain Sequences for d4x0ua_:

Sequence, based on SEQRES records:

>d4x0ua_ c.82.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
tllinqpqyawlkelglreenegvyngswggrgevittycpannepiarvrqasvadyee
tvkkareawkiwadipapkrgeivrqigdalrekiqvlgslvslemgkilvegvgevqey
vdicdyavglsrmiggpilpsersghalieqwnpvglvgiitafnfpvavygwnnaiami
cgnvclwkgapttslisvavtkiiakvlednklpgaicsltcggadigtamakdervnll
sftgstqvgkqvglmvqerfgrsllelggnnaiiafedadlslvvpsalfaavgtagqrc
ttarrlfihesihdevvnrlkkayaqirvgnpwdpnvlygplhtkqavsmflgaveeakk
eggtvvyggkvmdrpgnyveptivtglghdasiahtetfapilyvfkfkneeevfawnne
vkqglsssiftkdlgrifrwlgpkgsdcgivnvniptsgaeiggafggekhtgggresgs
dawkqymrrstctinyskdlplaqgikfq

Sequence, based on observed residues (ATOM records):

>d4x0ua_ c.82.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
tllinqpqyawlkelglreenegvyngswggrgevittycpannepiarvrqasvadyee
tvkkareawkiwadipapkrgeivrqigdalrekiqvlgslvslemgkilvegvgevqey
vdicdyavglsrmiggpilpsersghalieqwnpvglvgiitafnfpvavygwnnaiami
cgnvclwkgapttslisvavtkiiakvlednklpgaicsltcggadigtamakdervnll
sftgstqvgkqvglmvqerfgrsllelgnnaiiafedadlslvvpsalfaavgtagqrct
tarrlfihesihdevvnrlkkayaqirvgnpwdpnvlygplhtkqavsmflgaveeakke
ggtvvyggkvmdrpgnyveptivtglghdasiahtetfapilyvfkfkneeevfawnnev
kqglsssiftkdlgrifrwlgpkgsdcgivnvnisdawkqymrrstctinyqgikfq

Timeline for d4x0ua_:

• d4x0ua_ first appeared in SCOPe 2.05
  
• d4x0ua_ appears in SCOPe 2.07
  
• d4x0ua_ appears in the current release, SCOPe 2.08