Lineage for d4qsmd1 (4qsm D:2-160)

  1. Root: SCOPe 2.05
  2. 1815291Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 1826588Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 1826589Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 1829377Family c.2.1.5: LDH N-terminal domain-like [51848] (9 proteins)
  6. 1829416Protein Lactate dehydrogenase [51859] (17 species)
  7. 1829467Species Human (Homo sapiens), muscle isoform (M chain) [TaxId:9606] [63940] (13 PDB entries)
  8. 1829523Domain d4qsmd1: 4qsm D:2-160 [267355]
    Other proteins in same PDB: d4qsma2, d4qsmb2, d4qsmc2, d4qsmd2, d4qsme2, d4qsmf2, d4qsmg2, d4qsmh2
    automated match to d4l4ra1
    complexed with 38k

Details for d4qsmd1

PDB Entry: 4qsm (more details), 3 Å

PDB Description: crystal structure of human muscle l-lactate dehydrogenase in complex with inhibitor 2, 3-{[7-(2,4-dimethoxypyrimidin-5-yl)-3- sulfamoylquinolin-4-yl]amino}benzoic acid
PDB Compounds: (D:) L-lactate dehydrogenase A chain

SCOPe Domain Sequences for d4qsmd1:

Sequence; same for both SEQRES and ATOM records: (download)

>d4qsmd1 c.2.1.5 (D:2-160) Lactate dehydrogenase {Human (Homo sapiens), muscle isoform (M chain) [TaxId: 9606]}

SCOPe Domain Coordinates for d4qsmd1:

Click to download the PDB-style file with coordinates for d4qsmd1.
(The format of our PDB-style files is described here.)

Timeline for d4qsmd1: