SCOP 1.71: Domain d3tlha_: 3tlh A:

Lineage for d3tlha_ (3tlh A:)

1. Root: SCOP 1.71

2. Class b: All beta proteins [48724] (149 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (2 families)

5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (8 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

6. Protein Human immunodeficiency virus type 1 protease [50632] (1 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (179 PDB entries)

8. Domain d3tlha_: 3tlh A: [26609]
   complexed with inh

Details for d3tlha_

PDB Entry: 3tlh, 2 Å

PDB Description: structural studies of hiv and fiv proteases complexed withan efficient inhibitor of fiv pr

SCOP Domain Sequences for d3tlha_:

Sequence; same for both SEQRES and ATOM records:

>d3tlha_ b.50.1.1 (A:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1}
pqitlwkrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigctlnf

Timeline for d3tlha_:

• d3tlha_ first appeared (with stable ids) in SCOP 1.55
  
• d3tlha_ appears in SCOP 1.69
  
• d3tlha_ appears in SCOP 1.73
  
• d3tlha_ appears in the current release, SCOPe 2.08