SCOP 1.71: Domain d4phva_: 4phv A:

Lineage for d4phva_ (4phv A:)

1. Root: SCOP 1.71

2. Class b: All beta proteins [48724] (149 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (2 families)

5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (8 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

6. Protein Human immunodeficiency virus type 1 protease [50632] (1 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (179 PDB entries)

8. Domain d4phva_: 4phv A: [26607]

Details for d4phva_

PDB Entry: 4phv, 2.1 Å

PDB Description: x-ray crystal structure of the hiv protease complex with l-700,417, an inhibitor with pseudo c2 symmetry

SCOP Domain Sequences for d4phva_:

Sequence; same for both SEQRES and ATOM records:

>d4phva_ b.50.1.1 (A:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1}
pqitlwqrplvtikiggqlkealldtgaddtvleemnlpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigctlnf

Timeline for d4phva_:

• d4phva_ first appeared (with stable ids) in SCOP 1.55
  
• d4phva_ appears in SCOP 1.69
  
• d4phva_ appears in SCOP 1.73
  
• d4phva_ appears in the current release, SCOPe 2.08