Lineage for d1cu1b1 (1cu1 B:1705-1720,B:1003-1186)

  1. Root: SCOP 1.65
  2. 287094Class b: All beta proteins [48724] (126 folds)
  3. 298675Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 298676Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families) (S)
  5. 299596Family b.47.1.3: Viral proteases [50596] (4 proteins)
    beta sheet in the first domain is opened rather than forms a barrel
  6. 299597Protein NS3 protease [50600] (2 species)
  7. 299602Species Human hepatitis C virus (HCV), different isolates [TaxId:11103] [50601] (10 PDB entries)
  8. 299612Domain d1cu1b1: 1cu1 B:1705-1720,B:1003-1186 [26409]
    Other proteins in same PDB: d1cu1a2, d1cu1a3, d1cu1b2, d1cu1b3
    complexed with po4, zn

Details for d1cu1b1

PDB Entry: 1cu1 (more details), 2.5 Å

PDB Description: crystal structure of an enzyme complex from hepatitis c virus

SCOP Domain Sequences for d1cu1b1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1cu1b1 b.47.1.3 (B:1705-1720,B:1003-1186) NS3 protease {Human hepatitis C virus (HCV), different isolates}
gsvvivgriilsgsgsXitaysqqtrgllgciitsltgrdknqvegevqvvstatqsfla
tcvngvcwtvyhgagsktlagpkgpitqmytnvdqdlvgwqappgarsltpctcgssdly
lvtrhadvipvrrrgdsrgsllsprpvsylkgssggpllcpsghavgifraavctrgvak
avdfvpvesmettmrspvftd

SCOP Domain Coordinates for d1cu1b1:

Click to download the PDB-style file with coordinates for d1cu1b1.
(The format of our PDB-style files is described here.)

Timeline for d1cu1b1: