SCOPe 2.03: Domain d1fdpa_: 1fdp A:

Lineage for d1fdpa_ (1fdp A:)

1. Root: SCOPe 2.03

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (48 proteins)

6. Protein Factor D [50563] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50564] (12 PDB entries)

8. Domain d1fdpa_: 1fdp A: [26322]
   proenzyme

Details for d1fdpa_

PDB Entry: 1fdp, 2.1 Å

PDB Description: proenzyme of human complement factor d, recombinant profactor d

PDB Compounds: (A:) proenzyme of complement factor d

SCOPe Domain Sequences for d1fdpa_:

Sequence, based on SEQRES records:

>d1fdpa_ b.47.1.2 (A:) Factor D {Human (Homo sapiens) [TaxId: 9606]}
ilggreaeaharpymasvqlngahlcggvlvaeqwvlsaahcledaadgkvqvllgahsl
sqpepskrlydvlravphpdsqpdtidhdllllqlsekatlgpavrplpwqrvdrdvapg
tlcdvagwgivnhagrrpdslqhvllpvldratcnrrthhdgaiterlmcaesnrrdsck
gdsggplvcggvlegvvtsgsrvcgnrkkpgiytrvasyaawidsvla

Sequence, based on observed residues (ATOM records):

>d1fdpa_ b.47.1.2 (A:) Factor D {Human (Homo sapiens) [TaxId: 9606]}
ilggreaeaharpymasvqlngahlcggvlvaeqwvlsaahcledaadgkvqvllgahsl
sqpepskrlydvlravphpdsqpdtidhdllllqlsekatlgpavrplpwqrvdrdvapg
tlcdvagwgipdslqhvllpvldratcnrrthhdgaiterlmcaesnrrdsckgdsggpl
vcggvlegvvtsgsrvcgnrkkpgiytrvasyaawidsvla

Timeline for d1fdpa_:

• d1fdpa_ first appeared (with stable ids) in SCOP 1.55
  
• d1fdpa_ appears in SCOPe 2.02
  
• d1fdpa_ appears in SCOPe 2.04
  
• d1fdpa_ appears in the current release, SCOPe 2.08