SCOPe 2.04: Domain d4oowb_: 4oow B:

Lineage for d4oowb_ (4oow B:)

1. Root: SCOPe 2.04

2. Class e: Multi-domain proteins (alpha and beta) [56572] (68 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (7 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.4: RNA-dependent RNA-polymerase [56694] (3 proteins)

6. Protein Viral RNA polymerase [56695] (17 species)

7. Species Hepatitis c virus isolate [TaxId:420174] [188905] (16 PDB entries)

8. Domain d4oowb_: 4oow B: [261850]
   automated match to d3gnwb_
   complexed with caq

Details for d4oowb_

PDB Entry: 4oow, 2.57 Å

PDB Description: HCV NS5B polymerase with a fragment of quercetagetin

PDB Compounds: (B:) RNA-directed RNA polymerase

SCOPe Domain Sequences for d4oowb_:

Sequence, based on SEQRES records:

>d4oowb_ e.8.1.4 (B:) Viral RNA polymerase {Hepatitis c virus isolate [TaxId: 420174]}
smsytwtgalitpcaaeesklpinplsnsllrhhnmvyattsrsaslrqkkvtfdrlqvl
ddhyrdvlkemkakastvkakllsieeackltpphsakskfgygakdvrnlssravnhir
svwedlledtetpidttimaksevfcvqpekggrkparlivfpdlgvrvcekmalydvvs
tlpqavmgssygfqyspkqrveflvntwkskkcpmgfsydtrcfdstvtesdirveesiy
qccdlapearqairslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylkat
aacraaklqdctmlvngddlvvicesagtqedaaalrafteamtrysappgdppqpeydl
elitscssnvsvahdasgkrvyyltrdpttplaraawetarhtpinswlgniimyaptlw
armilmthffsillaqeqlekaldcqiygacysiepldlpqiierlhglsaftlhsyspg
einrvasclrklgvpplrtwrhrarsvrakllsqggraatcgrylfnwavrtklkltpip
aasqldlsgwfvagysggdiyh

Sequence, based on observed residues (ATOM records):

>d4oowb_ e.8.1.4 (B:) Viral RNA polymerase {Hepatitis c virus isolate [TaxId: 420174]}
smsytwtgalitpcaeellrhhnmvyattsrsaslrqkkvtfdrlqvlddhyrdvlkemk
akastvkakllsieeackltpphsakskfgygakdvrnlssravnhirsvwedlledtet
pidttimaksevfcvqrkparlivfpdlgvrvcekmalydvvstlpqavmgssygfqysp
kqrveflvntwkskkcpmgfsydtrcfdstvtesdirveesiyqccdlapearqairslt
erlyiggpltnskgqncgyrrcrasgvlttscgntltcylkataacraaklqdctmlvng
ddlvvicesagtqedaaalrafteamtrysappgdppqpeydlelitscssnvsvahdas
gkrvyyltrdpttplaraawetarhtpinswlgniimyaptlwarmilmthffsillaqe
qlekaldcqiygacysiepldlpqiierlhglsaftlhsyspgeinrvasclrklgvppl
rtwrhrarsvrakllsggraatcgrylfnwavrtklkltpiplsgwfvagysggdiyh

Timeline for d4oowb_:

• d4oowb_ is new in SCOPe 2.04-stable
  
• d4oowb_ appears in SCOPe 2.05
  
• d4oowb_ appears in the current release, SCOPe 2.08