SCOPe 2.04: Domain d3nj8b_: 3nj8 B:

Lineage for d3nj8b_ (3nj8 B:)

1. Root: SCOPe 2.04

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

6. Protein automated matches [190085] (43 species)
   not a true protein

7. Species Toxoplasma gondii [TaxId:5811] [261808] (1 PDB entry)

8. Domain d3nj8b_: 3nj8 B: [261810]
   automated match to d4o1mc_
   complexed with nad, nj8

Details for d3nj8b_

PDB Entry: 3nj8, 2.7 Å

PDB Description: Crystal structure of T. gondii enoyl acyl carrier protein reductase with bound triclosan like inhibitor

PDB Compounds: (B:) enoyl-acyl carrier reductase

SCOPe Domain Sequences for d3nj8b_:

Sequence, based on SEQRES records:

>d3nj8b_ c.2.1.2 (B:) automated matches {Toxoplasma gondii [TaxId: 5811]}
pidlrgqtafvagvadshgygwaiakhlasagarvalgtwppvlglfqkslqsgrldedr
klpdgsliefagvypldaafdkpedvpqdikdnkryagvdgytikevavkvkqdlgnidi
lvhslangpevtkplletsrkgylaassnsaysfvsllqhfgpimneggsavtlsylaae
rvvpgygggmssakaalesdtrtlaweagqkygvrvnaisagplksraasaigksgeksf
idyaidysynnaplrrdlhsddvggaalfllsplaravsgvtlyvdnglhamgqavdsrs
mpp

Sequence, based on observed residues (ATOM records):

>d3nj8b_ c.2.1.2 (B:) automated matches {Toxoplasma gondii [TaxId: 5811]}
pidlrgqtafvagvadshgygwaiakhlasagarvalgtwppvlglfqkslqsgrldedr
klpdgsliefagvypldaafdkpedvpqdikdnkryagvdgytikevavkvkqdlgnidi
lvhslangpevtkplletsrkgylaassnsaysfvsllqhfgpimneggsavtlsylaae
rvvpgygggmssakaalesdtrtlaweagqkygvrvnaisagplksraasaiksfidyai
dysynnaplrrdlhsddvggaalfllsplaravsgvtlyvdnglhamgqavdsrsmpp

Timeline for d3nj8b_:

• d3nj8b_ is new in SCOPe 2.04-stable
  
• d3nj8b_ appears in SCOPe 2.05
  
• d3nj8b_ appears in the current release, SCOPe 2.08