Lineage for d4wkia_ (4wki A:)

  1. Root: SCOPe 2.04
  2. 1631855Class d: Alpha and beta proteins (a+b) [53931] (380 folds)
  3. 1660634Fold d.92: Zincin-like [55485] (2 superfamilies)
    contains mixed beta sheet with connection over free side of the sheet
  4. 1660635Superfamily d.92.1: Metalloproteases ("zincins"), catalytic domain [55486] (18 families) (S)
  5. 1661658Family d.92.1.0: automated matches [191495] (1 protein)
    not a true family
  6. 1661659Protein automated matches [190805] (12 species)
    not a true protein
  7. 1661678Species Human (Homo sapiens) [TaxId:9606] [188286] (26 PDB entries)
  8. 1661691Domain d4wkia_: 4wki A: [261632]
    automated match to d3ljta_
    complexed with 3pw, ca, edo, zn

Details for d4wkia_

PDB Entry: 4wki (more details), 1.6 Å

PDB Description: crystal structure of human adamts-4 in complex with inhibitor 5-chloro-n-{[(4s)-4-(1-methyl-1h-imidazol-2-yl)-2,5-dioxoimidazolidin-4-yl]methyl}-1-benzofuran-2-carboxamide (compound 11)
PDB Compounds: (A:) A disintegrin and metalloproteinase with thrombospondin motifs 4

SCOPe Domain Sequences for d4wkia_:

Sequence, based on SEQRES records: (download)

>d4wkia_ d.92.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
slsrfvetlvvaddkmaafhgaglkrylltvmaaaakafkhpsirnpvslvvtrlvilgs
geegpqvgpsaaqtlrsfcawqrglntpedsdpdhfdtailftrqdlcgvstcdtlgmad
vgtvcdparscaiveddglqsaftaahelghvfnmlhdnskpcislngplstsrhvmapv
mahvdpeepwspcsarfitdfldngyghclldkpeaplhlp

Sequence, based on observed residues (ATOM records): (download)

>d4wkia_ d.92.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
slsrfvetlvvaddkmaafhgaglkrylltvmaaaakafkhpsirnpvslvvtrlvilgp
qvgpsaaqtlrsfcawqrglntpedsdpdhfdtailftrqdlcgvstcdtlgmadvgtvc
dparscaiveddglqsaftaahelghvfnmlhdnskpcislngplsrhvmapvmahvdpe
epwspcsarfitdfldngyghclldkpeaplhlp

SCOPe Domain Coordinates for d4wkia_:

Click to download the PDB-style file with coordinates for d4wkia_.
(The format of our PDB-style files is described here.)

Timeline for d4wkia_: