SCOPe 2.06: Domain d4ovnc_: 4ovn C:

Lineage for d4ovnc_ (4ovn C:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.39: EF Hand-like [47472] (4 superfamilies)
   core: 4 helices; array of 2 hairpins, opened

4. Superfamily a.39.1: EF-hand [47473] (12 families)
   Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop

5. Family a.39.1.5: Calmodulin-like [47502] (24 proteins)
   Duplication: made with two pairs of EF-hands

6. Protein Calmodulin [47516] (12 species)

7. Species Human (Homo sapiens) [TaxId:9606] [47517] (88 PDB entries)
   Uniprot P02593

8. Domain d4ovnc_: 4ovn C: [261374]
   automated match to d1iq5a_
   complexed with mg, po4, so4

Details for d4ovnc_

PDB Entry: 4ovn, 2.8 Å

PDB Description: voltage-gated sodium channel 1.5 (nav1.5) c-terminal domain in complex with calmodulin poised for activation

PDB Compounds: (C:) calmodulin

SCOPe Domain Sequences for d4ovnc_:

Sequence; same for both SEQRES and ATOM records:

>d4ovnc_ a.39.1.5 (C:) Calmodulin {Human (Homo sapiens) [TaxId: 9606]}
qlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgngt
idfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeevd
emireadidgdgqvnyeefvqmmta

Timeline for d4ovnc_:

• d4ovnc_ first appeared in SCOPe 2.04
  
• d4ovnc_ appears in SCOPe 2.05
  
• d4ovnc_ appears in SCOPe 2.07
  
• d4ovnc_ appears in the current release, SCOPe 2.08