Lineage for d4npta_ (4npt A:)

  1. Root: SCOPe 2.04
  2. 1510239Class b: All beta proteins [48724] (176 folds)
  3. 1548217Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 1548218Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. 1548219Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
    dimer of identical mono-domain chains, each containing (6,10) barrel
  6. 1548235Protein Human immunodeficiency virus type 1 protease [50632] (8 species)
  7. 1548442Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (432 PDB entries)
    Uniprot P35963 57-155 ! Uniprot P04587 69-167 ! Uniprot P03366 69-167 ! Uniprot P03367 69-167 ! Uniprot P03368 69-167
  8. 1548858Domain d4npta_: 4npt A: [260198]
    automated match to d3d1xa_
    complexed with 017, gol; mutant

Details for d4npta_

PDB Entry: 4npt (more details), 1.66 Å

PDB Description: Crystal Structure of HIV-1 Protease Multiple Mutant P51 Complexed with Darunavir
PDB Compounds: (A:) Protease

SCOPe Domain Sequences for d4npta_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4npta_ b.50.1.1 (A:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 [TaxId: 11676]}
pqitlwkrpivtikvggqlrealintgaddtifeeislpgrwkpkliggiggfmkvrqyd
qipieiaghkaigtvlvgptpinvigrnmltqigatlnf

SCOPe Domain Coordinates for d4npta_:

Click to download the PDB-style file with coordinates for d4npta_.
(The format of our PDB-style files is described here.)

Timeline for d4npta_: