SCOPe 2.04: Domain d4cwya_: 4cwy A:

Lineage for d4cwya_ (4cwy A:)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.174: Nitric oxide (NO) synthase oxygenase domain [56511] (1 superfamily)
   unusual fold

4. Superfamily d.174.1: Nitric oxide (NO) synthase oxygenase domain [56512] (1 family)
   automatically mapped to Pfam PF02898

5. Family d.174.1.1: Nitric oxide (NO) synthase oxygenase domain [56513] (2 proteins)

6. Protein automated matches [190421] (5 species)
   not a true protein

7. Species Cow (Bos taurus) [TaxId:9913] [188827] (15 PDB entries)

8. Domain d4cwya_: 4cwy A: [259343]
   automated match to d3e7sa_
   complexed with act, h4b, hem, hw1, zn

Details for d4cwya_

PDB Entry: 4cwy, 2.15 Å

PDB Description: structure of bovine endothelial nitric oxide synthase heme domain in complex with 6-(5-(((3r,4r)-4-((6-amino-4-methylpyridin-2-yl)methyl) pyrrolidin-3-yl)oxy)pentyl)-4-methylpyridin-2-amine

PDB Compounds: (A:) Nitric oxide synthase, endothelial

SCOPe Domain Sequences for d4cwya_:

Sequence, based on SEQRES records:

>d4cwya_ d.174.1.1 (A:) automated matches {Cow (Bos taurus) [TaxId: 9913]}
gpkfprvknwelgsitydtlcaqsqqdgpctprrclgslvlprklqtrpspgpppaeqll
sqardfinqyyssikrsgsqaheerlqeveaevastgtyhlreselvfgakqawrnaprc
vgriqwgklqvfdardcssaqemftyicnhikyatnrgnlrsaitvfpqrapgrgdfriw
nsqlvryagyrqqdgsvrgdpanveitelciqhgwtpgngrfdvlplllqapdeapelfv
lppelvlevplehptlewfaalglrwyalpavsnmlleigglefsaapfsgwymsteigt
rnlcdphryniledvavcmdldtrttsslwkdkaaveinlavlhsfqlakvtivdhhaat
vsfmkhldneqkarggcpadwawivppisgsltpvfhqemvnyilspafryqpdpw

Sequence, based on observed residues (ATOM records):

>d4cwya_ d.174.1.1 (A:) automated matches {Cow (Bos taurus) [TaxId: 9913]}
gpkfprvknwelgsitydtlcaqsqqdgpctprrclgslvlppaeqllsqardfinqyys
sikrsgsqaheerlqeveaevastgtyhlreselvfgakqawrnaprcvgriqwgklqvf
dardcssaqemftyicnhikyatnrgnlrsaitvfpqrapgrgdfriwnsqlvryagyrq
qdgsvrgdpanveitelciqhgwtpgngrfdvlplllqapdeapelfvlppelvlevple
hptlewfaalglrwyalpavsnmlleigglefsaapfsgwymsteigtrnlcdphrynil
edvavcmdldtrttsslwkdkaaveinlavlhsfqlakvtivdhhaatvsfmkhldneqk
arggcpadwawivppisgsltpvfhqemvnyilspafryqpdpw

Timeline for d4cwya_:

• d4cwya_ is new in SCOPe 2.04-stable
  
• d4cwya_ appears in SCOPe 2.05
  
• d4cwya_ appears in the current release, SCOPe 2.08