SCOPe 2.04: Domain d4cx3a_: 4cx3 A:

Lineage for d4cx3a_ (4cx3 A:)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.174: Nitric oxide (NO) synthase oxygenase domain [56511] (1 superfamily)
   unusual fold

4. Superfamily d.174.1: Nitric oxide (NO) synthase oxygenase domain [56512] (1 family)
   automatically mapped to Pfam PF02898

5. Family d.174.1.1: Nitric oxide (NO) synthase oxygenase domain [56513] (2 proteins)

6. Protein Nitric oxide (NO) synthase oxygenase domain [56514] (6 species)

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [82821] (169 PDB entries)
   Uniprot P29476 298-716

8. Domain d4cx3a_: 4cx3 A: [258905]
   automated match to d3hsob_
   complexed with act, gol, h4b, hem, hw8, zn; mutant

Details for d4cx3a_

PDB Entry: 4cx3, 1.97 Å

PDB Description: structure of rat neuronal nitric oxide synthase m336v d597n mutant heme domain in complex with 4-methyl-6-(((3r,4r)-4-((5-(pyridin-2-yl) pentyl)oxy)pyrrolidin-3-yl)methyl)pyridin-2-amine

PDB Compounds: (A:) Nitric oxide synthase, brain

SCOPe Domain Sequences for d4cx3a_:

Sequence, based on SEQRES records:

>d4cx3a_ d.174.1.1 (A:) Nitric oxide (NO) synthase oxygenase domain {Norway rat (Rattus norvegicus) [TaxId: 10116]}
rflkvknwetdvvltdtlhlkstletgctehicmgsivlpsqhtrkpedvrtkdqlfpla
kefldqyyssikrfgskahmdrleevnkeieststyqlkdteliygakhawrnasrcvgr
iqwsklqvfdardcttahgmfnyicnhvkyatnkgnlrsaitifpqrtdgkhdfrvwnsq
liryagykqpdgstlgdpanvqfteiciqqgwkaprgrfdvlplllqangndpelfqipp
elvlevpirhpkfdwfkdlglkwyglpavsnmlleigglefsacpfsgwymgteigvrny
cdnsrynileevakkmdldmrktsslwkdqalveiniavlysfqsdkvtivdhhsatesf
ikhmeneyrcrggcpadwvwivppmsgsitpvfhqemlnyrltpsfeyqpdpwnthvwk

Sequence, based on observed residues (ATOM records):

>d4cx3a_ d.174.1.1 (A:) Nitric oxide (NO) synthase oxygenase domain {Norway rat (Rattus norvegicus) [TaxId: 10116]}
rflkvknwetdvvltdtlhlkstletgctehicmgsivlptkdqlfplakefldqyyssi
krfgskahmdrleevnkeieststyqlkdteliygakhawrnasrcvgriqwsklqvfda
rdcttahgmfnyicnhvkyatnkgnlrsaitifpqrtdgkhdfrvwnsqliryagykqpd
gstlgdpanvqfteiciqqgwkaprgrfdvlplllqangndpelfqippelvlevpirhp
kfdwfkdlglkwyglpavsnmlleigglefsacpfsgwymgteigvrnycdnsrynilee
vakkmdldmrktsslwkdqalveiniavlysfqsdkvtivdhhsatesfikhmeneyrcr
ggcpadwvwivppmsgsitpvfhqemlnyrltpsfeyqpdpwnthvwk

Timeline for d4cx3a_:

• d4cx3a_ is new in SCOPe 2.04-stable
  
• d4cx3a_ appears in SCOPe 2.05
  
• d4cx3a_ appears in the current release, SCOPe 2.08