SCOPe 2.06: Domain d4bxaa_: 4bxa A:

Lineage for d4bxaa_ (4bxa A:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Protein kinase CK2, alpha subunit [56142] (3 species)
   CMGC group; CK2 subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [75559] (91 PDB entries)

8. Domain d4bxaa_: 4bxa A: [257739]
   automated match to d3wara_
   complexed with cl, gol, jrj, so4

Details for d4bxaa_

PDB Entry: 4bxa, 2.65 Å

PDB Description: tetragonal complex structure of protein kinase ck2 catalytic subunit with a benzotriazole-based inhibitor generated by click-chemistry

PDB Compounds: (A:) Casein kinase II subunit alpha

SCOPe Domain Sequences for d4bxaa_:

Sequence; same for both SEQRES and ATOM records:

>d4bxaa_ d.144.1.7 (A:) Protein kinase CK2, alpha subunit {Human (Homo sapiens) [TaxId: 9606]}
sgpvpsrarvytdvnthrpreywdyeshvvewgnqddyqlvrklgrgkysevfeainitn
nekvvvkilkpvkkkkikreikilenlrggpniitladivkdpvsrtpalvfehvnntdf
kqlyqtltdydirfymyeilkaldychsmgimhrdvkphnvmidhehrklrlidwglaef
yhpgqeynvrvasryfkgpellvdyqmydysldmwslgcmlasmifrkepffhghdnydq
lvriakvlgtedlydyidkynieldprfndilgrhsrkrwerfvhsenqhlvspealdfl
dkllrydhqsrltareamehpyfytvvkdqa

Timeline for d4bxaa_:

• d4bxaa_ first appeared in SCOPe 2.04
  
• d4bxaa_ appears in SCOPe 2.05
  
• d4bxaa_ does not appear in SCOPe 2.07