SCOPe 2.04: Domain d4l4ra2: 4l4r A:160-331

Lineage for d4l4ra2 (4l4r A:160-331)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.162: LDH C-terminal domain-like [56326] (1 superfamily)
   unusual fold, defines family

4. Superfamily d.162.1: LDH C-terminal domain-like [56327] (3 families)

5. Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain [56328] (5 proteins)
   N-terminal domain is NAD-binding module (alpha/beta Rossmann-fold domain)
   automatically mapped to Pfam PF02866

6. Protein Lactate dehydrogenase [56339] (19 species)

7. Species Homo sapiens [TaxId:9606] [256978] (1 PDB entry)

8. Domain d4l4ra2: 4l4r A:160-331 [256979]
   Other proteins in same PDB: d4l4ra1
   automated match to d5ldha2

Details for d4l4ra2

PDB Entry: 4l4r, 2.1 Å

PDB Description: structural characterisation of the apo-form of human lactate dehydrogenase m isozyme

PDB Compounds: (A:) L-lactate dehydrogenase A chain

SCOPe Domain Sequences for d4l4ra2:

Sequence; same for both SEQRES and ATOM records:

>d4l4ra2 d.162.1.1 (A:160-331) Lactate dehydrogenase {Homo sapiens [TaxId: 9606]}
sgcnldsarfrylmgerlgvhplschgwvlgehgdssvpvwsgmnvagvslktlhpdlgt
dkdkeqwkevhkqvvesayeviklkgytswaiglsvadlaesimknlrrvhpvstmikgl
ygikddvflsvpcilgqngisdlvkvtltseeearlkksadtlwgiqkelqf

Timeline for d4l4ra2:

• d4l4ra2 is new in SCOPe 2.04-stable
  
• d4l4ra2 appears in SCOPe 2.05
  
• d4l4ra2 appears in the current release, SCOPe 2.08