Lineage for d4j6ia2 (4j6i A:357-522)

  1. Root: SCOPe 2.05
  2. 1755445Class b: All beta proteins [48724] (176 folds)
  3. 1775883Fold b.7: C2 domain-like [49561] (5 superfamilies)
    sandwich; 8 strands in 2 sheets; greek-key
  4. 1775884Superfamily b.7.1: C2 domain (Calcium/lipid-binding domain, CaLB) [49562] (3 families) (S)
    two constituent families are related by circular permutation
  5. 1776107Family b.7.1.0: automated matches [191388] (1 protein)
    not a true family
  6. 1776108Protein automated matches [190497] (4 species)
    not a true protein
  7. 1776111Species Human (Homo sapiens) [TaxId:9606] [188711] (19 PDB entries)
  8. 1776124Domain d4j6ia2: 4j6i A:357-522 [252816]
    Other proteins in same PDB: d4j6ia1, d4j6ia3, d4j6ia4
    automated match to d1e8wa2
    complexed with 1jv

Details for d4j6ia2

PDB Entry: 4j6i (more details), 2.9 Å

PDB Description: Discovery of thiazolobenzoxepin PI3-kinase inhibitors that spare the PI3-kinase beta isoform
PDB Compounds: (A:) Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

SCOPe Domain Sequences for d4j6ia2:

Sequence, based on SEQRES records: (download)

>d4j6ia2 b.7.1.0 (A:357-522) automated matches {Human (Homo sapiens) [TaxId: 9606]}

Sequence, based on observed residues (ATOM records): (download)

>d4j6ia2 b.7.1.0 (A:357-522) automated matches {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d4j6ia2:

Click to download the PDB-style file with coordinates for d4j6ia2.
(The format of our PDB-style files is described here.)

Timeline for d4j6ia2: