SCOPe 2.04: Domain d4iqwa3: 4iqw A:303-510

Lineage for d4iqwa3 (4iqw A:303-510)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.218: Nucleotidyltransferase [81302] (1 superfamily)
   core: alpha-beta-turn-beta-X-beta-(alpha); mixed beta-sheet, order of core strands: 123

4. Superfamily d.218.1: Nucleotidyltransferase [81301] (16 families)

5. Family d.218.1.2: DNA polymerase beta-like [81300] (5 proteins)
   insert X in the core is an alpha-beta(2) unit; mixed 5-stranded sheet, order: 12543; contains extra C-terminal alpha+beta subdomain

6. Protein automated matches [254484] (3 species)
   not a true protein

7. Species Mouse (Mus musculus) [TaxId:10090] [256295] (17 PDB entries)

8. Domain d4iqwa3: 4iqw A:303-510 [252683]
   Other proteins in same PDB: d4iqwa1, d4iqwa2
   automated match to d1jmsa4
   protein/DNA complex; complexed with 1fq, na

Details for d4iqwa3

PDB Entry: 4iqw, 2.6 Å

PDB Description: tdt core in complex with inhibitor (2z,5e)-6-[4-(4-fluorobenzoyl)-1h- pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid and ssdna

PDB Compounds: (A:) DNA nucleotidylexotransferase

SCOPe Domain Sequences for d4iqwa3:

Sequence, based on SEQRES records:

>d4iqwa3 d.218.1.2 (A:303-510) automated matches {Mouse (Mus musculus) [TaxId: 10090]}
vnrpeaeavsmlvkeavvtflpdalvtmtggfrrgkmtghdvdflitspeatedeeqqll
hkvtdfwkqqglllycdilestfekfkqpsrkvdaadhfqkcflilkldhgrvhseksgq
qegkgwkairvdlvmcpydrrafallgwtgsrqferdlrryatherkmmldnhalydrtk
rvfleaeseeeifahlgldyiepwerna

Sequence, based on observed residues (ATOM records):

>d4iqwa3 d.218.1.2 (A:303-510) automated matches {Mouse (Mus musculus) [TaxId: 10090]}
vnrpeaeavsmlvkeavvtflpdalvtmtggfrrgkmtghdvdflitspeatedeeqqll
hkvtdfwkqqglllycdilestfekfkqpsrkdaadhfqkcflilkldhgrvhsekegkg
wkairvdlvmcpydrrafallgwtgsrqferdlrryatherkmmldnhalydrtkrvfle
aeseeeifahlgldyiepwerna

Timeline for d4iqwa3:

• d4iqwa3 is new in SCOPe 2.04-stable
  
• d4iqwa3 appears in SCOPe 2.05
  
• d4iqwa3 appears in the current release, SCOPe 2.08