SCOPe 2.06: Domain d4h34a1: 4h34 A:4-110

Lineage for d4h34a1 (4h34 A:4-110)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.93: SH2-like [55549] (1 superfamily)
   3 layers: a/b/a; antiparallel beta-sheet of 5 strands is flanked by two helices

4. Superfamily d.93.1: SH2 domain [55550] (2 families)

5. Family d.93.1.0: automated matches [191409] (1 protein)
   not a true family

6. Protein automated matches [190561] (4 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187549] (49 PDB entries)

8. Domain d4h34a1: 4h34 A:4-110 [252370]
   Other proteins in same PDB: d4h34a3
   automated match to d2shpa2
   complexed with edo, gol; mutant

Details for d4h34a1

PDB Entry: 4h34, 2.7 Å

PDB Description: crystal structure of the tyrosine phosphatase shp-2 with q506p mutation

PDB Compounds: (A:) Tyrosine-protein phosphatase non-receptor type 11

SCOPe Domain Sequences for d4h34a1:

Sequence, based on SEQRES records:

>d4h34a1 d.93.1.0 (A:4-110) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rrwfhpnitgveaenllltrgvdgsflarpsksnpgdftlsvrrngavthikiqntgdyy
dlyggekfatlaelvqyymehhgqlkekngdvielkyplncadptse

Sequence, based on observed residues (ATOM records):

>d4h34a1 d.93.1.0 (A:4-110) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rrwfhpnitgveaenllltrgvdgsflarpsksnpgdftlsvrrngavthikiqntgdyy
dlyggekfatlaelvqyymehhgqvielkyplncadptse

Timeline for d4h34a1:

• d4h34a1 first appeared in SCOPe 2.04
  
• d4h34a1 appears in SCOPe 2.05
  
• d4h34a1 appears in SCOPe 2.07
  
• d4h34a1 appears in the current release, SCOPe 2.08