SCOPe 2.06: Domain d4fo6a2: 4fo6 A:329-385

Lineage for d4fo6a2 (4fo6 A:329-385)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.60: SAM domain-like [47768] (16 superfamilies)
   4-5 helices; bundle of two orthogonally packed alpha-hairpins; involved in the interactions with DNA and proteins

4. Superfamily a.60.12: PsbU/PolX domain-like [81585] (3 families)
   contains one classic and one pseudo HhH motifs

5. Family a.60.12.1: DNA polymerase beta-like, second domain [81584] (3 proteins)
   topological similarity to the N-terminal domain
   automatically mapped to Pfam PF10391

6. Protein DNA polymerase lambda [101253] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [101254] (27 PDB entries)

8. Domain d4fo6a2: 4fo6 A:329-385 [252041]
   Other proteins in same PDB: d4fo6a1, d4fo6a3
   automated match to d1xsna2
   protein/DNA complex; complexed with cl, f2a, mg, mn, na

Details for d4fo6a2

PDB Entry: 4fo6, 2.01 Å

PDB Description: Crystal structure of the pre-catalytic ternary complex of polymerase lambda with a dATP analog opposite a templating T and an rCMP at the primer terminus.

PDB Compounds: (A:) DNA polymerase lambda

SCOPe Domain Sequences for d4fo6a2:

Sequence; same for both SEQRES and ATOM records:

>d4fo6a2 a.60.12.1 (A:329-385) DNA polymerase lambda {Human (Homo sapiens) [TaxId: 9606]}
sesvpvlelfsniwgagtktaqmwyqqgfrsledirsqaslttqqaiglkhysdfle

Timeline for d4fo6a2:

• d4fo6a2 first appeared in SCOPe 2.04
  
• d4fo6a2 appears in SCOPe 2.05
  
• d4fo6a2 appears in SCOPe 2.07
  
• d4fo6a2 appears in the current release, SCOPe 2.08