SCOPe 2.05: Domain d4e3xa_: 4e3x A:

Lineage for d4e3xa_ (4e3x A:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.82: ALDH-like [53719] (1 superfamily)
   consists of two similar domains with 3 layers (a/b/a) each; duplication
   core: parallel beta-sheet of 5 strands, order 32145

4. Superfamily c.82.1: ALDH-like [53720] (3 families)
   binds NAD differently from other NAD(P)-dependent oxidoreductases

5. Family c.82.1.0: automated matches [191448] (1 protein)
   not a true family

6. Protein automated matches [190683] (38 species)
   not a true protein

7. Species Mouse (Mus musculus) [TaxId:10090] [256133] (9 PDB entries)

8. Domain d4e3xa_: 4e3x A: [251653]
   automated match to d4oe5a_
   complexed with 16p, pge, pro

Details for d4e3xa_

PDB Entry: 4e3x, 1.24 Å

PDB Description: Crystal Structure of Mus musculus 1-pyrroline-5-carboxylate dehydrogenase cryoprotected in proline

PDB Compounds: (A:) Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial

SCOPe Domain Sequences for d4e3xa_:

Sequence; same for both SEQRES and ATOM records:

>d4e3xa_ c.82.1.0 (A:) automated matches {Mouse (Mus musculus) [TaxId: 10090]}
hmlrwkhtsslkvanepilafsqgsperdalqkalkdlkgqteaipcvvgdeevwtsdiq
yqlspfnhahkvakfcyadkallnraidaalaarkewdlkpmadraqvflkaadmlsgpr
raevlaktmvgqgktviqaeidaaaelidffrfnakfavelegeqpisvppstnhtvyrg
legfvaaispfnftaiggnlagapalmgnvvlwkpsdtamlasyavyrilreaglppnii
qfvpadgptfgdtvtssehlcginftgsvptfkhlwrqvaqnldrfrtfprlagecggkn
fhfvhssadvdsvvsgtlrsafeyggqkcsacsrlyvpkslwpqikgrlleehsrikvgd
paedfgtffsavidakafarikkwleharsspslsilaggqcnesvgyyvepciieskdp
qepimkeeifgpvltvyvypddkyretlklvdsttsygltgavfaqdkaivqeatrmlrn
aagnfyindkstgsvvgqqpfggarasgtndkpggphyilrwtspqvikethkplgdwry
sym

Timeline for d4e3xa_:

• d4e3xa_ first appeared in SCOPe 2.04
  
• d4e3xa_ is called d4e3xa1 in SCOPe 2.06
  
• d4e3xa_ appears in the current release, SCOPe 2.08, called d4e3xa1