SCOPe 2.04: Domain d3uwkb_: 3uwk B:

Lineage for d3uwkb_ (3uwk B:)

1. Root: SCOPe 2.04

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.0: automated matches [191323] (1 protein)
   not a true family

6. Protein automated matches [190123] (79 species)
   not a true protein

7. Species Pseudomonas aeruginosa [TaxId:208964] [226294] (7 PDB entries)

8. Domain d3uwkb_: 3uwk B: [250272]
   automated match to d3uwob_
   complexed with 0df, mg

Details for d3uwkb_

PDB Entry: 3uwk, 1.91 Å

PDB Description: Structure Guided Development of Novel Thymidine Mimetics targeting Pseudomonas aeruginosa Thymidylate Kinase: from Hit to Lead Generation

PDB Compounds: (B:) thymidylate kinase

SCOPe Domain Sequences for d3uwkb_:

Sequence, based on SEQRES records:

>d3uwkb_ c.37.1.0 (B:) automated matches {Pseudomonas aeruginosa [TaxId: 208964]}
glfvtlegpegagkstnrdylaerlrergievqltrepggtplaerirelllapsdepma
adtelllmfaaraqhlagvirpalargavvlcdrftdatyayqgggrglpeariaalesf
vqgdlrpdltlvfdlpveiglaraaargrldrfeqedrrffeavrqtylqraaqaperyq
vldaglplaevqagldrllpnllerl

Sequence, based on observed residues (ATOM records):

>d3uwkb_ c.37.1.0 (B:) automated matches {Pseudomonas aeruginosa [TaxId: 208964]}
glfvtlegpegagkstnrdylaerlrergievqltrepggtplaerirelllapsdepma
adtelllmfaaraqhlagvirpalargavvlcdrftdatyayqgggrglpeariaalesf
vqgdlrpdltlvfdlpveigdrfeqedrrffeavrqtylqraaqaperyqvldaglplae
vqagldrllpnllerl

Timeline for d3uwkb_:

• d3uwkb_ is new in SCOPe 2.04-stable
  
• d3uwkb_ appears in SCOPe 2.05
  
• d3uwkb_ appears in the current release, SCOPe 2.08