SCOPe 2.08: Domain d3tv8a2: 3tv8 A:324-421

Lineage for d3tv8a2 (3tv8 A:324-421)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.71: Glycosyl hydrolase domain [51010] (1 superfamily)
   folded sheet; greek-key

4. Superfamily b.71.1: Glycosyl hydrolase domain [51011] (6 families)
   this domain is C-terminal to the catalytic beta/alpha barrel domain

5. Family b.71.1.1: alpha-Amylases, C-terminal beta-sheet domain [51012] (22 proteins)
   this domain follows the catalytic beta/alpha barrel domain

6. Protein Melibiase [75020] (4 species)

7. Species Human (Homo sapiens) [TaxId:9606] [101919] (21 PDB entries)
   alpha-galactosidase A

8. Domain d3tv8a2: 3tv8 A:324-421 [250037]
   Other proteins in same PDB: d3tv8a1, d3tv8b1
   automated match to d3hg3a2
   complexed with 2pe, dgj, nag, so4

Details for d3tv8a2

PDB Entry: 3tv8, 2.64 Å

PDB Description: pharmacological chaperoning in human alpha-galactosidase

PDB Compounds: (A:) Alpha-galactosidase A

SCOPe Domain Sequences for d3tv8a2:

Sequence; same for both SEQRES and ATOM records:

>d3tv8a2 b.71.1.1 (A:324-421) Melibiase {Human (Homo sapiens) [TaxId: 9606]}
lgkqgyqlrqgdnfevwerplsglawavaminrqeiggprsytiavaslgkgvacnpacf
itqllpvkrklgfyewtsrlrshinptgtvllqlentm

Timeline for d3tv8a2:

• d3tv8a2 first appeared in SCOPe 2.04
  
• d3tv8a2 appears in SCOPe 2.07