SCOPe 2.05: Domain d3su5a_: 3su5 A:

Lineage for d3su5a_ (3su5 A:)

1. Root: SCOPe 2.05

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.3: Viral proteases [50596] (5 proteins)
   beta sheet in the first domain is opened rather than forms a barrel

6. Protein automated matches [190658] (4 species)
   not a true protein

7. Species Hepatitis C virus subtype 1a [TaxId:31646] [226463] (19 PDB entries)

8. Domain d3su5a_: 3su5 A: [249575]
   automated match to d3su1a_
   complexed with so4, su3, zn

Details for d3su5a_

PDB Entry: 3su5, 1.55 Å

PDB Description: crystal structure of ns3/4a protease variant d168a in complex with vaniprevir

PDB Compounds: (A:) NS3 protease, NS4A protein

SCOPe Domain Sequences for d3su5a_:

Sequence; same for both SEQRES and ATOM records:

>d3su5a_ b.47.1.3 (A:) automated matches {Hepatitis C virus subtype 1a [TaxId: 31646]}
shmasmkkkgsvvivgrinlsgdtayaqqtrgeegcqetsqtgrdknqvegevqivstat
qtflatsingvlwtvyhgagtrtiaspkgpvtqmytnvdkdlvgwqapqgsrsltpctcg
ssdlylvtrhadvipvrrrgdsrgsllsprpisylkgsaggpllcpaghavgifraavst
rgvakavafipveslettmrs

Timeline for d3su5a_:

• d3su5a_ first appeared in SCOPe 2.04
  
• d3su5a_ is called d3su5a1 in SCOPe 2.06
  
• d3su5a_ appears in the current release, SCOPe 2.08, called d3su5a1